Results 111 to 120 of about 346,399 (298)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

A parametric design framework for the mass customization of bicycle helmet

Heliyon
Cluster analysis of 3D head shapes plays a crucial role in the mass customization design of products related to the head. Head shapes exhibit variations across different races, and designing helmets exclusively for Chinese individuals cannot solely rely ...
Zhaohua Zhu, Yi Huang, Wenxuan Ji, Jintuo Zhu, Wenyu Wang   +4 more
doaj   +1 more source

Fermi Surface Nesting and Anomalous Hall Effect in Magnetically Frustrated Mn2PdIn

Advanced Functional Materials, EarlyView.
Mn2PdIn, a frustrated inverse Heusler alloy, showing electronic‐structure driven anomalous Hall effect with Weyl crossings, Fermi‐surface nesting and near‐zero magnetization ideal for low‐magnetization spintronics. Abstract Noncollinear magnets with near‐zero net magnetization and nontrivial bulk electronic topology hold significant promise for ...
Afsar Ahmed, Arnab Bhattacharya, Prashant Singh, Ajay Kumar, Tukai Singha, Anis Biswas, Yaroslav Mudryk, I. Das   +7 more
wiley   +1 more source

Reevaluating the Activity of ZIF‐8 Based FeNCs for Electrochemical Ammonia Production

Advanced Functional Materials, EarlyView.
Though receiving much attention, the field of electrochemical nitrogen reduction reaction (eNRR) to ammonia is marked by doubts about whether this reaction is possible in aqueous media. This work sheds light on this question for iron single‐atom on N‐doped carbon (FeNC) catalysts—a class of well‐known catalysts that is also worth testing for the sister
Caroline Schneider, S. Esmael Balaghi, Niklas Ortlieb, Patrick Elsaesser, Sima Heidari, Christopher S. Allen, Anna Fischer   +6 more
wiley   +1 more source

Universal In Situ Isotope Exchange Raman Spectroscopy (IERS) Methodology for Measuring Oxygen Surface Exchange Dynamics Using a Probe Layer

Advanced Functional Materials, EarlyView.
A bespoke multilayer thin film configuration has been designed, which overcomes the material dependency of conventional isotope exchange Raman spectroscopy (IERS). This universal IERS methodology is efficient, non‐destructive and provides additional structural information and time resolution, which can be further extended to various isotopic elements ...
Zonghao Shen, Francesco Chiabrera, Alexander Stangl, Laetitia Rapenne, Federico Baiutti, Carmen Jiménez, Albert Tarancón, Mónica Burriel   +7 more
wiley   +1 more source

Assessment of validity and reliability of Persian version of System Usability Scale (SUS) for traffic signs

Salāmat-i kār-i Īrān, 2017
Background and aims: Usability is the extent to which a system, product or service can be used by specified users to achieve specified goals with effectiveness, efficiency and satisfaction in a specified context of use.
Fereshteh Taheri, Amir Kavusi, Yoosef Faghihnia Torshozi, Ali Asghar Farshad, Mahnaz Saremi   +4 more
doaj  

Implementation of K-Means and Single Linkage on Types of Disabilities in East Java Province

Contemporary Mathematics and Applications (ConMathA)
The high number of people with disabilities is one of the problems faced by the Indonesian government, especially in Java Province. After West Java Province, East Java Province is in second place as the province with the highest rate of people with ...
Putri Amaningsih, Tony Yulianto, Faisol, Rica Amalia   +3 more
doaj   +1 more source

A new validity index for crisp clusters

Pattern Analysis and Applications, 2015
In this paper, a new cluster validity index which can be considered as a measure of the accuracy of the partitioning of data sets is proposed. The new index, called the STR index, is defined as the product of two components which determine changes of compactness and separability of clusters during a clustering process.
openaire   +1 more source