Results 41 to 50 of about 346,399 (298)

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Cluster ensemble selection based on validity index in evidence space

Tongxin xuebao, 2015
At first,the concept of evidence space was proposed to overcome the weakness of distance space for describing the complex structure of data sets.And then,the Davies-Bouldin index was extended based on the evidence space proposed.Meanwhile the label ...
Kai BI, Xiao-dan WANG, Ya-qiong XING
doaj   +2 more sources

How Many Clusters: A Validation Index for Arbitrary-Shaped Clusters

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2013
Clustering validation indexes are intended to assess the goodness of clustering results. Many methods used to estimate the number of clusters rely on a validation index as a key element to find the correct answer. This paper presents a new validation index based on graph concepts, which has been designed to find arbitrary shaped clusters by exploiting ...
Baya, Ariel Emilio, Granitto, Pablo Miguel   +1 more
openaire   +3 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Performance Evaluation of Line Symmetry-Based Validity Indices on Clustering Algorithms

Journal of Intelligent Systems, 2017
Finding the optimal number of clusters and the appropriate partitioning of the given dataset are the two major challenges while dealing with clustering. For both of these, cluster validity indices are used.
Kumar Vijay, Chhabra Jitender Kumar, Kumar Dinesh   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Observational Cosmology And The Cosmic Distance Duality Relation

, 2011
We study the validity of cosmic distance duality relation between angular diameter and luminosity distances. To test this duality relation we use the latest Union2 Supernovae Type Ia (SNe Ia) data for estimating the luminosity distance. The estimation of
Jain, Deepak, Jhingan, Sanjay, Nair, Remya   +2 more
core   +1 more source

Spatiotemporal correlations of handset-based service usages [PDF]

, 2012
We study spatiotemporal correlations and temporal diversities of handset-based service usages by analyzing a dataset that includes detailed information about locations and service usages of 124 users over 16 months.
AK Dey, AL Barabási, C Castellano, C Song, C Song, D Lazer, G Gan, G Krings, G Palla, H Falaki, H Kwak, H Verkasalo, HH Jo, J Candia, J Karikoski, J Karikoski, J Karikoski, J Park, J Reades, JP Bagrow, JP Eckmann, JP Onnela, K Lewis, L Kovanen, M Karsai, MC González, ME Smoot, N Aharony, N Eagle, N Eagle, N Eagle, P Nurmi, P Wang, R Montoliu, S Goyal, T Soikkeli, T Soikkeli   +36 more
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source