Results 51 to 60 of about 1,244,223 (283)
FLIS: Clustered Federated Learning Via Inference Similarity for Non-IID Data Distribution
Conventional federated learning (FL) approaches are ineffective in scenarios where clients have significant differences in the distributions of their local data.
Mahdi Morafah +3 more
doaj +1 more source
Spectral clustering with imbalanced data [PDF]
Spectral clustering (SC) and graph-based semi-supervised learning (SSL) algorithms are sensitive to how graphs are constructed from data. In particular if the data has proximal and unbalanced clusters these algorithms can lead to poor performance on well-known graphs such as $k$-NN, full-RBF, $ $-graphs.
Qian, Jing, Saligrama, Venkatesh
openaire +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Clustered Multitask Nonnegative Matrix Factorization for Spectral Unmixing of Hyperspectral Data
In this paper, the new algorithm based on clustered multitask network is proposed to solve spectral unmixing problem in hyperspectral imagery. In the proposed algorithm, the clustered network is employed.
Khoshsokhan, Sara +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Clustered photoplethysmogram pulse wave shapes and their associations with clinical data
Photopletysmography (PPG) is a non-invasive and well known technology that enables the recording of the digital volume pulse (DVP). Although PPG is largely employed in research, several aspects remain unknown.
Serena Zanelli +6 more
doaj +1 more source
Clustering categorical data streams
In this paper, we propose an efficient clustering algorithm for analyzing categorical data streams. It has been proved that the proposed algorithm uses small memory footprints. We provide empirical analysis on the performance of the algorithm in clustering both synthetic and real data streams.
He, Zengyou +3 more
openaire +2 more sources
We consider efficient estimation of the Euclidean parameters in a generalized partially linear additive models for longitudinal/clustered data when multiple covariates need to be modeled nonparametrically, and propose an estimation procedure based on a ...
Cheng, Guang +2 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

