Results 101 to 110 of about 1,375,944 (307)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
gagolews/clustering-benchmarks: clustering-benchmarks-v1.1.0
, 2022 1.1.0 (2022-09-17) The project's homepage was created. It is available at https://clustering-benchmarks.gagolewski.com. Python package clustering-benchmarks released on PyPI.
Marek Gagolewski
core +1 more source
Nuove Prospettive Tecnologiche e di Servizio per l'Aerospazio
GEOmedia, 2018 Advances in technology have split the space community to focus on the miniaturization of conventional satellites, making smaller satellites increasingly popular every day and in recent years several small satellites have been launched (nano, micro and ...
Giovanni Nicolai
doaj
Data Mining Application in Higher Learning Institutions
Informatics in Education, 2008 One of the biggest challenges that higher learning institutions face today is to improve the quality of managerial decisions. The managerial decision making process becomes more complex as the complexity of educational entities increase.
Naeimeh DELAVARI +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Clustering of Polysemic Words [PDF]
, 2007 Cicurel L, Bloehdorn S, Cimiano P. Clustering of Polysemic Words. In: Decker R, Lenz H-J, eds. Advances in Data Analysis: Proceedings of the 30th Annual Conference of the German Classification Society (GfKl). Studies in Classification, Data Analysis, and
Lenz, Hans-Joachim +4 more
core +1 more source
Clustering and Community Detection With Imbalanced Clusters
IEEE Transactions on Signal and Information Processing over Networks, 2017 Spectral clustering methods which are frequently used in clustering and community detection applications are sensitive to the specific graph constructions particularly when imbalanced clusters are present. We show that ratio cut (RCut) or normalized cut (NCut) objectives are not tailored to imbalanced cluster sizes since they tend to emphasize cut ...
Cem Aksoylar +2 more
openaire +3 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Analysis of Application of Cluster Descriptions in Space of Characteristic Image Features
Data, 2018 In this paper, we propose an investigation of the properties of structural image recognition methods in the cluster space of characteristic features. Recognition, which is based on key point descriptors like SIFT (Scale-invariant Feature Transform), SURF
Oleksii Gorokhovatskyi +2 more
doaj +1 more source