Results 81 to 90 of about 2,258,350 (284)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Physical Health Portrait and Intervention Strategy of College Students Based on Multivariate Cluster Analysis and Machine Learning

Applied Sciences
With the rapid development of society and technology, the physical health of university students has become a critical concern, influencing both individual well-being and the national talent pool.
Rong Guo, Rou Dong, Ni Lu, Lin Yu, Chaoxian Chen, Yonglin Che, Jiajin Zhang, Jianke Yang   +7 more
doaj   +1 more source

Subspace Clustering through Sub-Clusters

, 2018
The problem of dimension reduction is of increasing importance in modern data analysis. In this paper, we consider modeling the collection of points in a high dimensional space as a union of low dimensional subspaces. In particular we propose a highly scalable sampling based algorithm that clusters the entire data via first spectral clustering of a ...
Li, Weiwei, Hannig, Jan, Mukherjee, Sayan   +2 more
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Multidimensional Particle Swarm Optimization-Based Algorithm for Brain MRI Tumor Segmentation

Sensors
Particle Swarm Optimization (PSO) has been extensively applied to optimization tasks in various domains, including image segmentation. In this work, we present a clustering-based segmentation algorithm that employs a multidimensional variant of PSO ...
Zsombor Boga, Csanád Sándor, Péter Kovács   +2 more
doaj   +1 more source

Clustering technique and peer assessment in teaching writing recount text to junior high school students

ELT Forum: Journal of English Language Teaching, 2017
This study was conducted under the consideration of the observation in SMPN 39 Semarang that many students faced problems in learning to write a text.
Eka Yunita Widyawati, Novia Trisanti
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Synergy Between Machine Learning and Formal Concept Analysis for Crowd Detection

IEEE Access
To enhance public safety, crowd detection and prevention systems have essentially become a natural means to manage diverse crowded areas, such as urban settings, transportation hubs, and event venues.
Anas M. Al-Oraiqat, Oleksandr Drieiev, Sattam Almatarneh, Mohammadnoor Injadat, Karim A. Al-Oraiqat, Hanna Drieieva, Yassin M. Y. Hasan   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Customized normalization clustering meth-odology for consumers with heterogeneous characteristics

Advances in Distributed Computing and Artificial Intelligence Journal, 2018
The increasing use and development of renewable energy sources and distributed generation, brought several changes to the power system operation. Electricity markets worldwide are complex and dynamic environments with very particular characteristics ...
Catarina RIBEIRO, Tiago PINTO, Zita VALE, Jose BAPTISTA   +3 more
doaj   +1 more source