Results 71 to 80 of about 2,258,350 (284)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Profiling the Spatial Structure of London: From Individual Tweets to Aggregated Functional Zones
Knowledge discovery about people and cities from emerging location data has been an active research field but is still relatively unexplored. In recent years, a considerable amount of work has been developed around the use of social media data, most of ...
Chen Zhong +3 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A clustering algorithm for ipsative variables
The aim of this study is to introduce a new clustering method for ipsatives variables. This method can be used for nominals or ordinals variables for which responses must be mutually exclusive, and it is independent of data distribution.
Jesica Rubiano Moreno +3 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
23 pages, 6 ...
Yan, Donghui +2 more
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Fair Clustering Through Fairlets [PDF]
We study the question of fair clustering under the {\em disparate impact} doctrine, where each protected class must have approximately equal representation in every cluster.
Chierichetti, Flavio +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The acoustic repertoires of long-finned pilot whales (Globicephala melas) in the Mediterranean Sea are poorly understood. This study aims to create a catalogue of calls, analyse acoustic parameters, and propose a classification tree for future research ...
M. Poupard +4 more
doaj +1 more source

