Results 51 to 60 of about 1,420,828 (341)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Hierarchical clusters of lanthanide cluster plus gold cluster

Inorganic and Nano-Metal Chemistry, 2020
In this work, we provide a facile and valid one-pot synthesis method to create unreported hierarchical cluster of lanthanide cluster plus gold cluster (Ln-Au cluster), by introducing the ligands with bifunctional groups of carboxyl and sulfhydryl. The identities of Ln-Au clusters are fully characterized to be Ln7Au20 (MPCA)21 (Ln = Ce, 1; Eu, 2; Tb, 3;
Kai Zheng, Kai Zheng, Li Haoran, Zhi-Peng Zhao, Zeng Chenghui   +4 more
openaire   +2 more sources

Clustering of near clusters versus cluster compactness [PDF]

Monthly Notices of the Royal Astronomical Society, 1989
Les proprietes d'agencement des amas de Zwicky proches sont etudiees en utilisant la fonction de correlation angulaire a 2 points. Ces fonctions sont estimees pour les amas compacts et moyennement compacts, pour les amas ouverts et pour tous les amas de Zwicky ...
Yi-peng Jing, Yu Gao
openaire   +2 more sources

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

FEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley, Daniel H. Shain, Eric A. Klein   +2 more
wiley   +1 more source

Generalization of Clustering Agreements and Distances for Overlapping Clusters and Network Communities [PDF]

Data Mining and Knowledge Discovery: Volume 29, Issue 5 (2015), 2014
A measure of distance between two clusterings has important applications, including clustering validation and ensemble clustering. Generally, such distance measure provides navigation through the space of possible clusterings. Mostly used in cluster validation, a normalized clustering distance, a.k.a.
arxiv   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

FEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri, Haruka Tachibana, Daisuke Kawasaki, Taichi Chisuga, Toma Kashima, Shinya Fushinobu, Fumitaka Kudo, Tadashi Eguchi, Akimasa Miyanaga   +8 more
wiley   +1 more source

Strategies to minimize heterogeneity and optimize clinical trials in Acute Respiratory Distress Syndrome (ARDS): Insights from mathematical modelling

EBioMedicine, 2022
Summary: Background: Mathematical modelling may aid in understanding the complex interactions between injury and immune response in critical illness.
Sonu Subudhi, Chrysovalantis Voutouri, C. Corey Hardin, Mohammad Reza Nikmaneshi, Ankit B. Patel, Ashish Verma, Melin J. Khandekar, Sayon Dutta, Triantafyllos Stylianopoulos, Rakesh K. Jain, Lance L. Munn   +10 more
doaj  

ANALISIS SEGMENTASI PELANGGAN MENGGUNAKAN KOMBINASI RFM MODEL DAN TEKNIK CLUSTERING

JUTEI (Jurnal Terapan Teknologi Informasi), 2018
Intense competition in the business field motivates a small and medium enterprises (SMEs) to manage customer services to the maximal. Improve of customer royalty by grouping cunstomers into some of groups and determining appropriate and effective ...
Beta Estri Adiana, Indah Soesanti, Adhistya Erna Permanasari   +2 more
doaj   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Co-word analysis for the non-scientific information example of Reuters Business Briefings

Data Science Journal, 2006
Co-word analysis is based on a sociological theory developed by the CSI and the SERPIA (Callon, Courtial, Turner, 1991) in the mid eighties. This method, originally dedicated to scientific fields, measures the association strength between terms in ...
B Delecroix, R Eppstein
doaj   +1 more source