Results 71 to 80 of about 2,744,930 (320)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Usage of clustering methods for sequence plan optimization in steel production

open access: yesMetalurgija, 2016
The paper deals with production scheduling of heat sequences while are steel types casted on continuous casting device. For production scheduling are used k-means clustering and fuzzy clustering methods.
P. Švec, L. Frischerová, J. David
doaj  

Simple Measures of Individual Cluster-Membership Certainty for Hard Partitional Clustering

open access: yes, 2018
We propose two probability-like measures of individual cluster-membership certainty which can be applied to a hard partition of the sample such as that obtained from the Partitioning Around Medoids (PAM) algorithm, hierarchical clustering or k-means ...
Graham, Jinko, Liu, Dongmeng
core   +2 more sources

Monopoles and Clusters [PDF]

open access: yesCommunications in Mathematical Physics, 2008
We define and study certain hyperkaehler manifolds which capture the asymptotic behaviour of the SU(2)-monopole metric in regions where monopoles break down into monopoles of lower charges. The rate at which these new metrics approximate the monopole metric is exponential, as for the Gibbons-Manton metric.
Roger Bielawski, Roger Bielawski
openaire   +5 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The process of clustering in Russia: dynamics and regional features of development

open access: yesЖурнал Белорусского государственного университета: География, геология, 2017
This article analyzes the characteristics of the formation of clusters and cluster policy in Russia’s regions. Improving the efficiency of the organization of the economic territory of the space – is the most important problem of the modern development ...
Tatiana F. Krejdenko   +2 more
doaj  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Profiling the Spatial Structure of London: From Individual Tweets to Aggregated Functional Zones

open access: yesISPRS International Journal of Geo-Information, 2018
Knowledge discovery about people and cities from emerging location data has been an active research field but is still relatively unexplored. In recent years, a considerable amount of work has been developed around the use of social media data, most of ...
Chen Zhong   +3 more
doaj   +1 more source

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