Results 171 to 180 of about 2,131,360 (300)

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

A new hybrid optimization approach using PSO, Nelder-Mead Simplex and Kmeans clustering algorithms for 1D Full Waveform Inversion. [PDF]

PLoS One, 2022
Aguiar Nascimento R, Neto ÁB, Bezerra YSF, do Nascimento HAD, Lucena LDS, de Freitas JE.   +5 more
europepmc   +1 more source

Coordination‐Modulated Catalytic Pathways at Carbon Dots‐Supported Single‐Atom Sites Revealed by Thiol Interactions

Advanced Functional Materials, EarlyView.
Carbon dots‐supported single‐atom catalysts provide a model platform for uncovering how coordination interactions regulate catalytic reactivity. Thiol binding at Ru‒N4 centers reshapes the reaction energy landscape of H2O2 activation, dynamically modulating ROS‐generation pathways through electronic‐structure perturbation.
Yihong Chen, Li Zhang, Qian Dong, Qingshi Liu, Kun Wang, Huiping Wang, Shaomin Shuang, Chuan Dong, Jin‐Chang Guo, Xiaojuan Gong, Zhuo Chen, Yingfu Li   +11 more
wiley   +1 more source

Multiple Clustering Algorithms for Ovarian Cancer Subtyping (MCAOCS): identifying clinical phenotypes and treatment response in critical care. [PDF]

J Ovarian Res
Qiu Y, Qin Z, Zheng H, Wang T, Liu R, Yang J.   +5 more
europepmc   +1 more source

Establishment and application of risk classification model for lead in vegetables based on spectral clustering algorithms. [PDF]

Food Sci Nutr, 2022
Jiang TQ, Wang Z, Zhang QC, Wang ZZ, Cheng BL.   +4 more
europepmc   +1 more source

Disorder‐Broadened Topological Hall Phase and Anomalous Hall Scaling in FeGe

Advanced Functional Materials, EarlyView.
By systematically introducing defects into FeGe via ion‐beam modification, we demonstrate that disorder broadens the temperature regime over which the topological Hall effect ‐ a signature of skyrmions or other chiral textures — appears, while also increasing its magnitude.
Chaman Gupta, Chris Matsumura, Hongbin Yang, Sarah Edwards, Rebeca M. Gurrola, Jiun‐Haw Chu, Hanjong Paik, Yongqiang Wang, David A. Muller, Robert Streubel, Tzu‐Ming Lu, Serena Eley   +11 more
wiley   +1 more source

Network clustering algorithms and preprocessing pipelines for robust cell type identification in single-cell RNA sequencing data. [PDF]

Sci Rep
Nasrollahi FSF, Silva FN, Liu S, Chaudhuri S, Yu M, Wang J, Nho K, Saykin AJ, Bennett DA, Sporns O, Fortunato S.   +10 more
europepmc   +1 more source

Quantitative Investigation of Acoustic Emission Waveform Parameters from Crack Opening in a Rail Section Using Clustering Algorithms and Advanced Signal Processing. [PDF]

Sensors (Basel), 2022
Mahajan H, Banerjee S.
europepmc   +1 more source

Load Distributing Metamaterials Via Discrete Optimization

Advanced Functional Materials, EarlyView.
Mechanical metamaterials are computationally optimized to homogenize transmitted forces by minimizing the spread of reaction forces. The resulting architectures transform localized loading into broader, more uniform force distributions and experimentally demonstrate robust load spreading under quasi‐static and impact loading.
Andrea Detry, Hannes Holey, Raja Zulkarnain, Roberto Guerra, Ilaria Papa, Michael Zaiser, Stefano Zapperi   +6 more
wiley   +1 more source

Testing network clustering algorithms with natural language processing. [PDF]

Front Artif Intell
Achitouv I, Chavalarias D, Gaume B.
europepmc   +1 more source