Results 71 to 80 of about 24,216,023 (259)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Correlation Clustering [PDF]

open access: yes, 2008
Knowledge Discovery in Databases (KDD) is the non-trivial process of identifying valid, novel, potentially useful, and ultimately understandable patterns in data.
Zimek, Arthur
core   +1 more source

Novel role analysis method for network domain users

open access: yes网络与信息安全学报, 2017
A novel role analysis method for network domain users was proposed.Firstly,the algorithm used ISODATA algorithm to cluster network events for user behavior analysis,on the basis of conditions,the method search relationships between varieties of grouping ...
Xiao-feng XU, Li YANG, Wei WANG
doaj  

Sensitivity Analysis of Time Length of Photovoltaic Output Power to Capacity Configuration of Energy Storage Systems

open access: yesEnergies, 2017
Time interval and time length are two important indexes when analyzing the active output data of photovoltaic (PV) power stations. When the time interval is constant, the length of time is too small, and the included information is less, resulting in a ...
Mingqi Wang, Xinqiao Zheng
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A rate of convergence in clustering analysis. [PDF]

open access: yes
We present a result about stochastic boundedness of stable empirical processes on Vapnik-Cervonenkis classes of functions and we apply it to obtain a rate of convergence for the approximation between the sample and the populational variation in the k ...
Romo, Juan
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Clustering documents with active learning using Wikipedia [PDF]

open access: yes, 2008
Wikipedia has been applied as a background knowledge base to various text mining problems, but very few attempts have been made to utilize it for document clustering. In this paper we propose to exploit the semantic knowledge in Wikipedia for clustering,
Ian H. Witten   +7 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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