Results 121 to 130 of about 3,155,909 (302)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Knowledge and practices towards rabies and determinants of dog rabies vaccination in households: a cross sectional study in an area with high dog bite incidents in Kakamega County, Kenya, 2013

open access: yesThe Pan African Medical Journal, 2014
BACKGROUND: an estimated 55,000 people die from rabies annually. Factors promoting dog vaccination, estimates of vaccination coverage and knowledge on rabies are important for effective rabies control. We sought to establish these estimates at household (
Gerald Mburu Mucheru   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Kinetics of clusters formation and accumulation in crystal under cascade-generating irradiation [PDF]

open access: yesЯдерна фізика та енергетика, 2011
Formation of point defect clusters under cascade-generating irradiation is theoretically investigated. Steady-state size distribution of cluster and its dependence on parameters is obtained.
M. V. Kobets   +2 more
doaj  

Large-Scale Errors In CCD Photometry of M67

open access: yesOpen Astronomy, 2003
The accuracy of new CCD photometry in the Vilnius system of the M67 cluster is analyzed. The observational material is obtained during six observing runs in 1994-2001 with the 1 meter telescope of the USNO Flagstaff Station.
Laugalys V.   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Perspectives and Distinctive Particularities of Collaborative Networks [PDF]

open access: yesRevista de Management Comparat International, 2012
Intra and extra organizational collaboration has become an important factor in increasing organizational competitiveness and regional ones. Technical and technological progress and the knowledge economy have led to the emergence of collaborative networks.
Alexandru Ionuţ ROJA, Marian NĂSTASE
doaj  

Tracing Galaxy Evolution by Their Present-Day Luminosity Function

open access: yesOpen Astronomy, 2011
Galaxy luminosity functions are derived for different morphological types and various colors of galaxies, to trace the evolutionary effects which a priori should be different for void and supercluster galaxies.
Tempel E.
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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