Results 201 to 210 of about 1,758,281 (314)

Disordered vacancy-isolated Ce-Gd-O clusters achieve exceptional low-temperature oxygen-ion conductivity for fuel cells. [PDF]

Sci Adv
Pang S, He X, Lou H, Xu K, Guan J, Zhuang Y, Luo X, Xu L, Xiao Q, Gao Y, Zhang P, Yang J, Li Y, Chen C.   +13 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Structural Evolution, Electronic, Bonding, and Magnetic Properties of Ti₂B_n (n = 2-16) Clusters: A Computational Study. [PDF]

Chemphyschem
Wang W, Wang B, Lian L, Xu S, Wang K.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

A high-resolution functional network-organized atlas of human superficial white matter from ultra-high-field diffusion MRI. [PDF]

iScience
He Y, Xie Y, Yip H, Hong Y, Wu Y.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Spatiotemporal co-circulation of four dengue serotypes across Mexico, 2020-2025: A space-time scan analysis. [PDF]

PLoS One
Mendoza-Cano O, Trujillo X, Ríos-Silva M, Bricio-Barrios JA, Lugo-Radillo A, Tapia-Vargas R, Venegas-Ramírez J, Ríos-Bracamontes EF, Cuevas-Arellano HB, Cárdenas Y, Aquino-Santos R, Jiménez-Vieyra IA, Uribe-Ramos JM, Benites-Godínez V, Martínez-Díaz TE, López-Rojas M, García-Solórzano A, Murillo-Zamora E.   +17 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Stability of Some Ternary 13-Atom Icosahedral Clusters Assessed with Geometric, Electronic, and Thermodynamic Criteria. [PDF]

J Phys Chem A
Krishnadas A, Tomaz Palheta JM, Bekele Mekonnen J, Parreira RLT, Mamani Flores E, Fournier R, Piotrowski MJ.   +6 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source