Results 121 to 130 of about 35,673 (235)

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 218-241, February 2026.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Program Synthesis using Natural Language [PDF]

, 2015
Interacting with computers is a ubiquitous activity for millions of people. Repetitive or specialized tasks often require creation of small, often one-off, programs. End-users struggle with learning and using the myriad of domain-specific languages (DSLs)
Aditya Desai, Amey Karkare, Mark Marron, Msr Redmond, Msr Redmond, Nidhi Jain, Roy, Sailesh R Subhajit, Sumit Gulwani, Vineet Hingorani   +9 more
core   +1 more source

Identification of Extracellular Vesicle Signatures of Daratumumab Treated Multiple Myeloma

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Multiple myeloma peripheral blood extracellular vesicles (EVs) are a source of non‐invasive biomarkers with potential for routine monitoring and to complement or replace invasive bone marrow biopsy. In this study, five proteins were significantly different from healthy controls and three associated with long‐term response on Daratumumab which may have ...
Kieran Brennan, Katrine F. Iversen, Alfonso Blanco‐Fernández, Thomas Lund, Torben Plesner, Margaret M. Mc Gee   +5 more
wiley   +1 more source

Regional Warehouse Trip Production Analysis: Chicago Metro Area [PDF]

, 2008
This research report provides primary research data and analysis on heavy truck trip generation and characteristics from regional distribution centers (RDC) and similar facilities in an effort to facilitate future public policy making regarding roadway ...
Dermisi, Sofia V., DeVries, Jon B.
core  

Risk Factors of Sural Nerve Axonal Degeneration Using Clinically Relevant Thresholds in Context of Glucose Metabolism: The Maastricht Study

Muscle &Nerve, Volume 73, Issue 2, Page 283-291, February 2026.
ABSTRACT Introduction/Aims To study the association of risk factors with axonal degeneration, based on below‐threshold sural nerve amplitudes, as a proxy for distal symmetric polyneuropathy (DSP). In particular, to assess the differential contribution of risk factors in diabetes status subgroups.
Jurriaan J. A. Hodzelmans, Marcus L. F. Janssen, Jos P. H. Reulen, Annemarie Koster, Nicolaas C. Schaper, Werner H. Mess, Nadia A. Sutedja   +6 more
wiley   +1 more source

Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues

Small Methods, Volume 10, Issue 3, 9 February 2026.
This review summarizes recent advances in nongenetic optoelectronic technologies for the modulation of excitable biotissues, covering material selection, device design, and working principles, as well as characterization methods. Representative applications in in vitro and in vivo models of the cardiac, central, and peripheral nervous systems are ...
Qi Wang, Jinghua Li
wiley   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

VIEW, Volume 7, Issue 1, February 2026.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin   +8 more
wiley   +1 more source

A new method for the estimation of motor nerve conduction block [PDF]

, 2007
Dario Cocito, Enoka, Farina, Feasby, Gazzoni, Kimura, Kimura, Luca Mesin, Oh, Olney, Reutskiy, Rhee, Rosenfalck, Schoonhoven, Schulte-Mattler, Schulte-Mattler, Stalberg, Tani, Tikhonov, Troni, Van Asseldonk   +20 more
core   +1 more source

DeepRec: Global Terrestrial Water Storage Reconstruction Since 1941 Using Spatiotemporal‐Aware Deep Learning Model

Journal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 1, February 2026.
Abstract Terrestrial water storage (TWS) plays an important role in describing the Earth system, as water availability is decisive for ecosystems and human development. Since 2002, the Gravity Recovery and Climate Experiment (GRACE) and its Follow‐On (GRACE‐FO) mission have measured TWS anomalies with unprecedented accuracy, enabling a leap in ...
Luis Q. Gentner, Junyang Gou, Mohammad J. Tourian, Lara Börger, Nico Sneeuw, Benedikt Soja   +5 more
wiley   +1 more source

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 310-320, February 2026.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi, Takeshi Osonoi, Norio Takahashi, Toru Takiguchi, Eiichiro Morishima, Yoshimasa Aso, Kenji Sekiguchi, Hideki Kamiya, Jiro Nakamura   +8 more
wiley   +1 more source