Results 91 to 100 of about 125,744 (212)

3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes

open access: yesThe FEBS Journal, EarlyView.
Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut   +2 more
wiley   +1 more source

Teach Me How to PyCap: A High‐Capacity Well Decision Support Tool Using Analytical Solutions in Python

open access: yesGroundwater, EarlyView.
Regulatory agencies in humid temperate environments rely on timely evaluations of streamflow depletion and drawdown to protect aquatic ecosystems and existing water users. We present an open‐source Python package implementing analytical solutions for estimating streamflow depletion and drawdown and supporting superposition of multiple wells and ...
Michael N. Fienen   +2 more
wiley   +1 more source

AI Mimicry and Human Dignity: Chatbot Use as a Violation of Self‐Respect

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT This article investigates how human interactions with AI‐powered chatbots may offend human dignity. Current chatbots, driven by large language models, mimic human linguistic behaviour but lack the moral and rational capacities essential for genuine interpersonal respect.
Jan‐Willem van der Rijt   +2 more
wiley   +1 more source

CMD Section Committees [PDF]

open access: yesEurophysics News, 1987
openaire   +1 more source

Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial

open access: yesJournal of the American Geriatrics Society, EarlyView.
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Adriana Abizanda Saro   +86 more
wiley   +1 more source

Tongue and Hyoid Bone Positions and Its Relations to the Mandibular Anterior Teeth: A Cone‐Beam Computed Tomography Study

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objectives This study aimed to investigate the position of the tongue and hyoid bone at rest according to incisal relationships using cone beam computed tomography and to examine whether dentoskeletal measurements are correlated with these positions.
Hieu Nguyen   +4 more
wiley   +1 more source

Alternaria alternata Effector Aa593 Promotes Virulence by Hijacking the CmNAC29‐Mediated Abscisic Acid Biosynthesis Pathway in Chrysanthemum

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The interaction between plants and pathogens has long been an actively researched field of plant immunity. In this study, we found an Aa593/CmNAC29‐CmNCED3 module associated with the interaction between chrysanthemum and the fungal pathogen Alternaria alternata.
Boxiao Dong   +10 more
wiley   +1 more source

An Ustilaginoidea virens Nuclear Effector SCRE7 Inhibits Rice Immunity via Suppressing OsLBD11/12‐Promoted Transcription of OsCPS2

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Phytopathogenic fungi secrete a great number of effector proteins into various organelles of host plants and suppress plant immunity through different mechanisms. In this study, we identify SCRE7 as a unique nuclear effector that is essential for U. virens infection.
Chunquan Jiang   +13 more
wiley   +1 more source

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