Results 1 to 10 of about 49,357 (117)

Circulating Biomarkers in Coronary Microvascular Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in the diagnosis and management of coronary ...
Teja Chakrala, Roshni Prakash, Carlos Valdes, Carl J. Pepine, Ellen C. Keeley   +4 more
doaj   +3 more sources

Single Nucleotide Polymorphisms in Coronary Microvascular Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. There are data to suggest that coronary microvascular dysfunction, in some cases, may be genetically determined.
Andrew P. Stein, Jonathan Harder, Henry R. Holmes, C. Noel Bairey Merz, Carl J. Pepine, Ellen C. Keeley   +5 more
doaj   +3 more sources

Immunometabolic Mechanisms of Coronary Microvascular Dysfunction in Coronary Artery Disease: The Role of Mitochondrial Stress, Endothelial Senescence, and Regulated Cell Death [PDF]

Cells
Chronic coronary syndromes (CCSs) are increasingly recognized as complex immunometabolic vascular disorders in which coronary microvascular dysfunction (CMD), persistent low-grade inflammation, oxidative stress, and maladaptive cellular remodeling ...
Mateusz Lucki, Ewa Lucka, Przemysław Mitkowski, Maciej Lesiak   +3 more
doaj   +2 more sources

Coronary Microvascular Dysfunction: Epidemiology, Clinical Presentation, Diagnosis and Treatment

Рациональная фармакотерапия в кардиологии, 2023
In a significant number of patients with symptoms of angina pectoris or myocardial infarction with ischemic changes in the myocardium, according to the results of instrumental research methods, there is no hemodynamically significant stenosis of the ...
E. L. Trisvetova
doaj   +1 more source

INOCA/ANOCA: Mechanisms and novel treatments

American Heart Journal Plus, 2023
Angina or ischemia with no obstructive coronary disease (ANOCA/INOCA) is a common but under-treated condition due to poorly understood pathophysiologic mechanisms, limited diagnostic tools, and lack of proven targeted therapy.
Namrita D. Ashokprabhu, Odayme Quesada, Yulith Roca Alvarez, Timothy D. Henry   +3 more
doaj   +1 more source

Role of coronary microvascular dysfunction in heart failure with preserved ejection fraction [PDF]

Reviews in Cardiovascular Medicine, 2021
Heart failure with preserved ejection fraction (HFpEF) is one of the greatest unmet needs in modern medicine. The lack of an appropriate therapy may reflect the lack of an accurate comprehension of its pathophysiology.
Francesco Tona, Roberta Montisci, Laura Iop, Giovanni Civieri   +3 more
doaj   +1 more source

Paradoxical coronary vasospasm and transient apical ballooning in a post-menopausal woman: An imaging case report of an unusual INOCA presentation

American Heart Journal Plus, 2022
Ischemia with non-obstructive coronary artery disease (INOCA), a common cause of angina, can occur due to coronary vasospasm, microvascular dysfunction, endothelial dysfunction, atherosclerosis or a combination of these mechanisms.
Madhavi Kadiyala, Saikrishna Patibandla, Erin D. Michos   +2 more
doaj   +1 more source

A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension

American Heart Journal Plus, 2023
Microvascular dysfunction progressing to pulmonary hypertension can be a primary cause of right ventricular failure or a secondary cause because of an underlying systemic illness.
Cyrus Vahdatpour, Samuel Epstein, Kirk Jones, Madeline Smoot, Alex Parker, John Ryan, Andrew Bryant   +6 more
doaj   +1 more source

Coronary endothelial dysfunction appears to be a manifestation of a systemic process: A report from the Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction (WISE-CVD) study.

PLoS ONE, 2021
BackgroundCoronary microvascular dysfunction (CMD) is prevalent in symptomatic women with ischemia but no obstructive coronary artery disease (INOCA). Urine albumin-creatinine ratio (UACR) is a measure of renal microvascular endothelial dysfunction. Both
Sawan Jalnapurkar, Sofy Landes, Janet Wei, Puja K Mehta, Chrisandra Shufelt, Margo Minissian, Carl J Pepine, Eileen Handberg, Galen Cook-Wiens, George Sopko, C Noel Bairey Merz   +10 more
doaj   +1 more source

Coronary microvascular dysfunction as a chronic inflammatory state: Is there a role for omega-3 fatty acid treatment?

American Heart Journal Plus, 2022
Coronary microvascular dysfunction is a ubiquitous pathologic process that is operational in ischemia with no obstructive coronary artery disease and other cardiovascular disorders including heart failure with preserved ejection fraction. It may, in fact,
Ellen C. Keeley, Eileen M. Handberg, Janet Wei, C. Noel Bairey Merz, Carl J. Pepine   +4 more
doaj   +1 more source