Results 41 to 50 of about 48,842 (275)

Invasive evaluation of coronary microvascular dysfunction [PDF]

open access: yesJournal of Nuclear Cardiology, 2022
Coronary microvascular dysfunction (CMD) is a prevalent cause of ischemic heart disease and is associated with poorer quality of life and worse patient outcomes. Both functional and structural abnormalities of the microcirculation can generate ischemia in the absence of epicardial stenosis or worsen concomitant obstructive coronary artery disease (CAD).
Travieso, Alejandro   +5 more
openaire   +4 more sources

Radionuclide imaging methods in the diagnosis of microvascular dysfunction in non-obstructive coronary artery disease

open access: yesРоссийский кардиологический журнал, 2022
Non-obstructive coronary artery disease is generally considered as a favorable type of pathology, however, a number of studies indicate that in non-obstructive atherosclerosis, the risk of such cardiovascular events as myocardial infarction, ischemic ...
A. N. Maltseva   +4 more
doaj   +1 more source

P27 Prevalence of microvascular dysfunction in diabetic patients with normal gated spect

open access: yesRevista de la Sociedad Argentina de Diabetes, 2020
Introduction: Patients with diabetes have an increased risk for cardiovascular events. Microvascular dysfunction is an early sign of damage, associated with poorer prognosis in these patients, including those with normal gated SPECT.
Hugo Daniel Sanabria   +7 more
doaj   +1 more source

MRI-based in vivo detection of coronary microvascular dysfunction before alterations in cardiac function induced by short-term high-fat diet in mice

open access: yesScientific Reports, 2021
Endothelial dysfunction is one of the hallmarks of vascular abnormalities in metabolic diseases and has been repeatedly demonstrated in coronary and peripheral circulation in mice fed high-fat diet (HFD), particularly after long-term HFD.
Grzegorz Kwiatkowski   +3 more
doaj   +1 more source

Microvascular Dysfunction in Patients With Type II Diabetes Mellitus: Invasive Assessment of Absolute Coronary Blood Flow and Microvascular Resistance Reserve

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Coronary microvascular dysfunction (CMD) is an early feature of diabetic cardiomyopathy, which usually precedes the onset of diastolic and systolic dysfunction.
Emanuele Gallinoro   +27 more
doaj   +1 more source

MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes

open access: yesCardiovascular Diabetology, 2022
Background Type 2 diabetes (T2D) is associated with coronary microvascular dysfunction, which is thought to contribute to compromised diastolic function, ultimately culminating in heart failure with preserved ejection fraction (HFpEF).
Shawn Veitch   +27 more
doaj   +1 more source

Fluoroscopic methods of assessment of coronary microvascular dysfunction – a review of literature [PDF]

open access: yesБългарска кардиология
A large proportion of patients with angina and evidence of myocardial ischemia do not have obstructive coronary disease. One of the main mechanisms of ischemia/angina with non-obstructive coronary arteries is coronary microvascular dysfunction, which is ...
R. Grigorov, S. Yambolov
doaj   +3 more sources

Adipsin alleviates cardiac microvascular injury in diabetic cardiomyopathy through Csk-dependent signaling mechanism

open access: yesBMC Medicine, 2023
Background Microvascular complications are associated with an overtly increased risk of adverse outcomes in patients with diabetes including coronary microvascular injury which manifested as disruption of adherens junctions between cardiac microvascular ...
Xuebin Zhang   +11 more
doaj   +1 more source

Pathophysiology and Diagnosis of Coronary Functional Abnormalities

open access: yesEuropean Cardiology Review, 2021
Approximately one-half of patients undergoing diagnostic coronary angiography for angina have no significant coronary atherosclerotic stenosis. This clinical condition has recently been described as ischaemia with non-obstructive coronary arteries (INOCA)
Jun Takahashi   +5 more
doaj   +1 more source

ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]

open access: yes, 1997
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Weber, Christian   +6 more
core   +1 more source

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