Results 51 to 60 of about 48,842 (275)

Classification, Diagnosis, and Treatment of Coronary Microvascular Dysfunction [PDF]

, 2022
Coronary microvascular dysfunction represents a widespread disease which is highly disabling for the patient, who constantly presents angina [...
Madaudo, Cristina, Galassi, Alfredo Ruggero, Alfredo Ruggero Galassi, Sucato, Vincenzo, Cristina Madaudo, Vincenzo Sucato   +5 more
core   +1 more source

Adipose-derived cells improve left ventricular diastolic function and increase microvascular perfusion in advanced age. [PDF]

PLoS ONE, 2018
An early manifestation of coronary artery disease in advanced age is the development of microvascular dysfunction leading to deficits in diastolic function.
Natia Q Kelm, Jason E Beare, Fangping Yuan, Monika George, Charles M Shofner, Bradley B Keller, James B Hoying, Amanda J LeBlanc   +7 more
doaj   +1 more source

Outpatient Management of Patients With Angina With No Obstructive Coronary Arteries: How to Come to a Proper Diagnosis and Therapy

Frontiers in Cardiovascular Medicine, 2021
Two-thirds of women and one-third of men who undergo a clinically indicated coronary angiography for stable angina, have no obstructive coronary artery disease (CAD). Coronary vascular dysfunction is a highly prevalent underlying cause of angina in these
Joan G. Meeder, Mariëlle J. Hartzema-Meijer, Tijn P. J. Jansen, Regina E. Konst, Peter Damman, Suzette E. Elias-Smale   +5 more
doaj   +1 more source

Sex Differences in Coronary Function Test Results in Patient With Angina and Nonobstructive Disease

Frontiers in Cardiovascular Medicine, 2021
Introduction: Invasive coronary function testing (CFT) has become the recommended diagnostic tool to assess the various endotypes of coronary vasomotor dysfunction in patients with angina and no obstructive coronary artery disease (ANOCA), which has ...
Tijn P. J. Jansen, Suzette E. Elias-Smale, Stijn van den Oord, Helmut Gehlmann, Aukelien Dimitiriu-Leen, Angela H. E. M. Maas, Regina E. Konst, Niels van Royen, Peter Damman   +8 more
doaj   +1 more source

Coronary microvascular dysfunction is associated with poor glycemic control amongst female diabetics with chest pain and non-obstructive coronary artery disease

Cardiovascular Diabetology, 2019
Background Patients with type 2 diabetes mellitus are at an increased risk of adverse cardiovascular events compared to those without diabetes. The timing, relative to disease onset, and degree of glycemic control that reduces the risk of adverse ...
Jaskanwal D. Sara, Riad Taher, Nikhil Kolluri, Adrian Vella, Lilach O. Lerman, Amir Lerman   +5 more
doaj   +1 more source

Prevention of Coronary Microvascular Obstruction by Addressing the Individual Susceptibility [PDF]

, 2018
Another pathogenetic component of coronary microvascular obstruction (CMVO) is constituted by the individual susceptibility to microvascular dysfunction, probably related to the function, as well as to the structure and the density of the ...
Giancarla Scalone, Giampaolo Niccoli, Scalone G., Niccoli G.   +3 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Impaired Coronary and Renal Vascular Function in Spontaneously Type 2 Diabetic Leptin-Deficient Mice. [PDF]

PLoS ONE, 2015
Type 2 diabetes is associated with macro- and microvascular complications in man. Microvascular dysfunction affects both cardiac and renal function and is now recognized as a main driver of cardiovascular mortality and morbidity.
Helena U Westergren, Julia Grönros, Suvi E Heinonen, Tasso Miliotis, Karin Jennbacken, Alan Sabirsh, Anette Ericsson, Ann-Cathrine Jönsson-Rylander, Sara Svedlund, Li-Ming Gan   +9 more
doaj   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Obesity and the microvasculature [PDF]

, 2013
Overweight and obesity are thought to significantly influence a person's risk of cardiovascular disease, possibly via its effect on the microvasculature.
Gopinath, Bamini, Tai, E. Shyong, Zoungas, Sophia, Boillot, Adrien, Brazionis, Laima, Klein, Ronald, Neubauer, Aljoscha Steffen, Hercberg, Serge, Czernichow, Sébastien, Wong, Tien-Yin, Mitchell, Paul, Klein, Barbara, Wang, Jie Jin, Saw, Seang-Mei, Ikram, Mohammad Kamran, Klaver, Caroline   +15 more
core   +1 more source