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Coronary microvascular dysfunction is a ubiquitous pathologic process that is operational in ischemia with no obstructive coronary artery disease and other cardiovascular disorders including heart failure with preserved ejection fraction. It may, in fact,
Ellen C. Keeley +4 more
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Pathophysiology of Coronary Microvascular Dysfunction
Ischemic heart disease (IHD) is commonly recognized as the consequence of coronary atherosclerosis and obstructive coronary artery disease (CAD). However, a significant number of patients may present angina or myocardial infarction even in the absence of any significant coronary artery stenosis and impairment of the coronary microcirculation has been ...
Crea, Filippo +2 more
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Background It remains unknown whether the presence of coronary microcirculatory dysfunction (CMD) correlates with its equivalent conditionin the brain, cerebral small vessel disease (CSVD).
de Diego, Jose Juan Gomez +32 more
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Background A significant proportion of patients with spontaneous coronary artery dissection (SCAD) have ongoing chronic chest pain despite healing of their dissection.
Tara Sedlak +3 more
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Heart failure with preserved ejection fraction (HFpEF) has been recognized as the greatest single unmet need in cardiovascular medicine. Indeed, the morbi-mortality of HFpEF is high and as the population ages and the comorbidities increase, so ...
Lauriane Cornuault +4 more
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Coronary microvascular dysfunction in heart failure patients [PDF]
Coronary microcirculation has multiple layers of autoregulatory function to maintain resting flow and augment hyperemic flow in response to myocardial demands.
Takumi Toya +4 more
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Pharmacotherapy for coronary microvascular dysfunction [PDF]
Coronary microvascular dysfunction (CMD) has been increasingly recognized as an important cardiac condition that can cause signs and symptoms of myocardial ischaemia in various clinical settings. The dysfunction is located on the level of the coronary microcirculation with a vessel diameter of
Peter, Ong +2 more
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Chest pain is a common clinical symptom, especially in patients with sickle cell anemia. Owing to the vast differential diagnosis, investigation can be challenging.
Kofi Tekyi Asamoah
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Coronary Microvascular Dysfunction, Microvascular Angina, and Management [PDF]
Recent analyses have found that coronary microvascular dysfunction (CMD) portends a poor prognosis in patients with and without obstructive epicardial coronary artery disease (CAD). Chest pain in the absence of epicardial CAD is a common entity. Angina caused by CMD, microvascular angina (MVA), is often indistinguishable from that caused by obstructive
Adrián I, Löffler, Jamieson M, Bourque
openaire +2 more sources
Backgroud: Diastolic dysfunction (DD) is reported to affect up to 35% of the adult general population. The consequence of progressive DD is heart failure with preserved ejection fraction (HFpEF).
Davies, Thomas +16 more
core +1 more source

