INOCA/ANOCA: Mechanisms and novel treatments
Angina or ischemia with no obstructive coronary disease (ANOCA/INOCA) is a common but under-treated condition due to poorly understood pathophysiologic mechanisms, limited diagnostic tools, and lack of proven targeted therapy.
Odayme Quesada, Namrita D Ashokprabhu
exaly +5 more sources
Magnetocardiography in the diagnosis of suspected ANOCA: a case series [PDF]
Patients with angina pectoris with non-obstructive coronary artery disease (ANOCA) often present to cardiology outpatient clinic or emergency departments with manifestations mimicking acute coronary syndrome (ACS).
Xiaoyan Xue +41 more
doaj +3 more sources
The Incremental Prognostic Value of Hyperemic Coronary Flow Velocity in Patients with Angina and Nonobstructive Coronary Artery Disease [PDF]
Risk stratification in patients with angina and nonobstructive coronary arteries (ANOCA) remains suboptimal. Coronary flow velocity reserve (CFVR) is prognostic but susceptible to hemodynamic variability; we evaluated whether hyperemic coronary flow ...
Quande Liu +10 more
doaj +3 more sources
Comprehensive Endotyping of Patients With Angina and Nonobstructive Coronary Arteries: A Report From the J‐CMD [PDF]
Background Angina with nonobstructive coronary arteries (ANOCA) is frequently driven by coronary vasospasm and coronary microvascular dysfunction (CMD).
Masahiro Hada +18 more
doaj +2 more sources
Angina and Non-Obstructive Coronary Artery (ANOCA) Patients with Coronary Vasomotor Disorders
Angina and Non-Obstructive Coronary Artery (ANOCA) patients often lack a clear explanation for their symptoms, and are frequently discharged with the label of “unspecified chest pain”, despite the availability of functional coronary angiography ...
Christopher Zeitz, John F Beltrame
exaly +3 more sources
Functional coronary vascular disease: endotype-based classification, diagnosis, and targeted management [PDF]
BackgroundAngina and exertional dyspnea are hallmark manifestations of coronary artery disease (CAD), traditionally linked to obstructive epicardial lesions.
Omar El Khatib +3 more
doaj +2 more sources
Development and cross-site validation of machine-learning models for diagnosis and prognosis of stable angina with and without obstructive coronary artery disease: a study protocol [PDF]
Introduction Angina with no obstructive coronary artery disease (ANOCA) affects millions and is frequently under-recognised because diagnostic pathways and risk tools predominantly target obstructive coronary artery disease (CAD). This protocol describes
Todd Anderson +10 more
doaj +2 more sources
Association between coronary vasomotor dysfunction and autoimmune disease in patients undergoing invasive coronary function testing [PDF]
Background: Autoimmune diseases (AD) are associated with increased cardiovascular risk, but their relationship with coronary vasomotor dysfunction (CVDys) in patients with angina with nonobstructive coronary arteries (ANOCA) remains unclear.
Nida Latif +10 more
doaj +2 more sources
Women’s IschemiA TRial to Reduce Events In Non-ObstRuctive CAD (WARRIOR): a randomised controlled trial [PDF]
Importance Women with angina due to suspected ischaemia referred for coronary angiography often have no obstructive coronary artery disease (ANOCA/INOCA).Objective To determine if intensive medical treatment (IMT) reduces major ischaemic events (major ...
Janet Wei +14 more
doaj +2 more sources
Association of reduced Cu,Zn-superoxide dismutase with coronary microvascular dysfunction-An observational study of oxidative stress markers- [PDF]
Background: Coronary microvascular dysfunction (CMD) is increasingly recognized as a key contributor to angina and non-obstructive coronary arteries (ANOCA) and adverse cardiovascular outcomes.
Koichi Sato +15 more
doaj +2 more sources

