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Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification [PDF]

open access: yesScientific Reports, 2018
Endothelial dysfunction contributes to sepsis outcome. Metabolic phenotypes associated with endothelial dysfunction are not well characterised in part due to difficulties in assessing endothelial metabolism in situ.
Sarah McGarrity   +8 more
doaj   +3 more sources

Endothelial dysfunction: molecular mechanisms and clinical implications

open access: yesMedComm
Cardiovascular disease (CVD) and its complications are a leading cause of death worldwide. Endothelial dysfunction plays a crucial role in the initiation and progression of CVD, serving as a pivotal factor in the pathogenesis of cardiovascular, metabolic,
Xia Wang, Ben He
doaj   +2 more sources

Endothelial dysfunction reversibility [PDF]

open access: yesVojnosanitetski Pregled, 2007
Coronary artery disease, the leading cause of morbidity and mortality, is a continuum of events that can lead to end stage heart disease . Common to the pathogenesis of most cardiovascular diseases are the processes, called risk factors for atherosclerotic coronary artery disease, that cause pathologic change and dysfunction in the blood vessels and ...
Obrenović-Kirćanski Biljana B.
doaj   +3 more sources

Biomarkers of endothelial activation and dysfunction in cardiovascular diseases [PDF]

open access: yesReviews in Cardiovascular Medicine, 2022
Endothelial activation and dysfunction is an important contributor to atherosclerosis, cardiovascular diseases and cardiorenal syndrome. Endothelial dysfunction is also linked with metabolic syndrome and type II diabetes.
Jun Zhang
doaj   +1 more source

Cerebral and systemic endothelial dysfunction in migraine: Current knowledge and perspective [PDF]

open access: yesRomanian Journal of Neurology, 2021
Migraine still causes a high rate of disability and is reported to increase the risk of cardiovascular and cerebrovascular diseases. Endothelial dysfunction is considered to be one of the underlying mechanisms linking migraine and vascular disorders ...
I Made Oka Adnyana   +1 more
doaj   +1 more source

Endothelial dysfunction: developmental mechanisms and therapeutic strategies [PDF]

open access: yesResearch Results in Pharmacology, 2022
Introduction: Every year the importance of the normal functioning of the endothelial layer of the vascular wall in maintaining the health of the body becomes more and more obvious.
Dmitry V. Shcheblykin   +7 more
doaj   +3 more sources

Endothelial Dysfunction [PDF]

open access: yesJournal of the American Society of Nephrology, 2004
Endothelial dysfunction is characterized by a shift of the actions of the endothelium toward reduced vasodilation, a proinflammatory state, and prothrombic properties. It is associated with most forms of cardiovascular disease, such as hypertension, coronary artery disease, chronic heart failure, peripheral artery disease, diabetes, and chronic renal ...
Dierk H, Endemann, Ernesto L, Schiffrin
openaire   +2 more sources

PHARMACOLOGICAL EFFICIENCY OF STATINS AND L-NORVALIN AT AN ENDOTOXIN-INDUCED ENDOTHELIAL DYSFUNCTION [PDF]

open access: yesResearch Results in Pharmacology, 2016
In the animals with endotoxin-induced endothelial dysfunction there were imbalance of contractile response of vessels wall observes when carrying out functional tests, increase of coefficient of endothelial dysfunction, decrease in contractility of a ...
Inna Ivlitskaya   +2 more
doaj   +3 more sources

Endothelial dysfunction in patients with chronic obstructive pulmonary disease: some aspects of medicamental treatment (a literature review)

open access: yesZaporožskij Medicinskij Žurnal, 2021
The aim of the study was to analyze the professional literature concerning general principles of medicamental correction for endothelial dysfunction and their peculiarities in patients with chronic obstructive pulmonary disease.
O. I. Lemko, N. V. Vantiukh
doaj   +1 more source

T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea. [PDF]

open access: yes, 2013
BackgroundObstructive sleep apnea (OSA) is a low-grade inflammatory disease affecting the cardiovascular and metabolic systems. Increasing OSA severity reduces T-regulatory lymphocytes (Tregs) in OSA children. Since Tregs modulate endothelial activation,
Bandla, Hari PR   +8 more
core   +17 more sources

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