Results 41 to 50 of about 635,820 (301)

Endothelin and endothelial dysfunction

Proceedings of the Japan Academy, Series B, 2006
Nitric oxide (NO) and endothelin (ET) produced in endothelial cells are leading molecules which regulate vascular function. Failure of the physiological balance between these two molecules is usually referred to as endothelial dysfunction. ET was initially identified as a potent vasoconstrictive peptide. Three ET isoforms and two ET receptors have been
Tomoh, Masaki, Tatsuya, Sawamura
openaire   +3 more sources

Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress. [PDF]

, 2017
Sirtuin1 (Sirt1) is a class III histone deacetylase that regulates a variety of physiological processes, including endothelial function. Caveolin1 (Cav1) is also an important determinant of endothelial function. We asked if Sirt1 governs endothelial Cav1
Gabani, Mohanad, Irani, Kaikobad, Jacobs, Julia S, Kassan, Adam, Kassan, Modar, Kim, Young-Rae, Kumar, Santosh, Li, Qiuxia, Liu, Jing, Patel, Hemal H, Vikram, Ajit   +10 more
core   +7 more sources

Endothelial Function in Dyslipidemia: Roles of LDL-Cholesterol, HDL-Cholesterol and Triglycerides

Cells, 2023
Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial step for atherosclerosis, resulting in cardiovascular complications.
Yukihito Higashi
doaj   +1 more source

Method of treating endothelial dysfunction comprising administration of a thrombin peptide derivative [PDF]

, 2012
Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.Board of Regents, University of ...
Carney, Darrell H., Fossum, Theresa W., Olszewska-Pazdrak, Barbara   +2 more
core   +1 more source

Overview of the Assessment of Endothelial Function in Humans

Frontiers in Medicine, 2020
The endothelium is recognized to play an important role in various physiological functions including vascular tone, permeability, anticoagulation, and angiogenesis.
Po Ying Chia, Po Ying Chia, Po Ying Chia, Andrew Teo, Andrew Teo, Tsin Wen Yeo, Tsin Wen Yeo, Tsin Wen Yeo   +7 more
doaj   +1 more source

Exercise Improves Endothelial Function via the lncRNA MALAT1/miR-320a Axis in Obese Children and Adolescents

Cardiology Research and Practice, 2021
Background. Endothelial dysfunction commonly occurs in obese children and adolescents, leading to an increased risk of cardiovascular diseases. Exercise has significant protective effects against endothelial dysfunction through regulating some noncoding ...
Wei Zhao, Yane Yin, Huiling Cao, Yandong Wang   +3 more
doaj   +1 more source

Effective treatment of edema and endothelial barrier dysfunction with imatinib [PDF]

, 2012
Background-Tissue edema and endothelial barrier dysfunction as observed in sepsis and acute lung injury carry high morbidity and mortality, but currently lack specific therapy.
Aman, J., Bezu, J. van, Damanafshan, A., Eringa, E.C., Groeneveld, A.B.J., Hinsbergh, V.W.M. van, Huveneers, S., Nieuw Amerongen, G.P. van, Vogel, S.M., Vonk Noordegraaf, A.   +9 more
core   +1 more source

The association between endothelial dysfunction and subclinical myocardial injury in male obstructive sleep apnoea patients

ERJ Open Research
Background Endothelial dysfunction was shown to contribute significantly to the elevated cardiovascular risk observed in the general population. However, the relationship between endothelial dysfunction and subclinical myocardial injury in obstructive ...
Wenhao Cao, Jinmei Luo, Xinjie Hui, Yi Xiao, Rong Huang   +4 more
doaj   +1 more source

Endothelial dysfunction assessed by brachial artery flow-mediated dilatation predicts severe COVID-19-related disease

Journal of Family Medicine and Primary Care, 2022
Background: Endothelial dysfunction, inflammation, and hypercoagulability are hallmarks of severe COVID-19 related disease. Endothelial function can be measured non-invasively by flow-mediated dilatation in the brachial artery.
Rohit Walia, Venkat Subaih Arunachalam, Udit Chauhan, Meenakshi Khapre, Poonam Arora   +4 more
doaj   +1 more source

Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis

Scientific Reports, 2017
Despite the associations between diabetic complications and vascular endothelial dysfunction, a direct therapeutic method targeting endothelial dysfunction remains poorly characterized.
Kumiko Taguchi, Mari Hida, Mami Hasegawa, Haruka Narimatsu, Takayuki Matsumoto, Tsuneo Kobayashi   +5 more
doaj   +1 more source