Results 21 to 30 of about 403,263 (261)

Testing for endothelial dysfunction

Annals of Medicine, 2000
Endothelial health is a key factor in normal cardiovascular homeostasis, and recent studies have revealed several important functions of the vascular endothelium that protect against atherothrombosis. These include control over arterial tone, coagulation, fibrinolysis, and vascular growth. Consequently, endothelial dysfunction has been implicated as an
O T, Raitakari, D S, Celermajer
openaire   +2 more sources

The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission

Redox Biology, 2018
The accumulation of uremic toxins in chronic kidney disease (CKD) induces inflammation, oxidative stress and endothelial dysfunction, which is a key step in atherosclerosis.
Mengjie Huang, Ribao Wei, Yang Wang, Tingyu Su, Ping Li, Xiangmei Chen   +5 more
doaj   +1 more source

Endothelial Dysfunction and the Effect of Arginine and Citrulline Supplementation in Children and Adolescents With Mitochondrial Diseases

Journal of Central Nervous System Disease, 2020
Background: In addition to the reduced energy production, characteristic of mitochondrial disorders, nitric oxide (NO) deficiency can occur as well. The NO produced by vascular endothelial cells relaxes vascular smooth muscles, resulting in vasodilation ...
Fatma Al Jasmi, Nuha Al Zaabi, Khalid Al-Thihli, Amal M Al Teneiji, Jozef Hertecant, Ayman W El-Hattab   +5 more
doaj   +1 more source

Endothelin and endothelial dysfunction

Proceedings of the Japan Academy, Series B, 2006
Nitric oxide (NO) and endothelin (ET) produced in endothelial cells are leading molecules which regulate vascular function. Failure of the physiological balance between these two molecules is usually referred to as endothelial dysfunction. ET was initially identified as a potent vasoconstrictive peptide. Three ET isoforms and two ET receptors have been
MASAKI, Tomoh, SAWAMURA, Tatsuya
openaire   +3 more sources

Overview of the Assessment of Endothelial Function in Humans

Frontiers in Medicine, 2020
The endothelium is recognized to play an important role in various physiological functions including vascular tone, permeability, anticoagulation, and angiogenesis.
Po Ying Chia, Po Ying Chia, Po Ying Chia, Andrew Teo, Andrew Teo, Tsin Wen Yeo, Tsin Wen Yeo, Tsin Wen Yeo   +7 more
doaj   +1 more source

Significance of Endothelial Dysfunction Amelioration for Sodium–Glucose Cotransporter 2 Inhibitor-Induced Improvements in Heart Failure and Chronic Kidney Disease in Diabetic Patients

Metabolites, 2023
Beyond lowering plasma glucose levels, sodium–glucose cotransporter 2 inhibitors (SGLT2is) significantly reduce hospitalization for heart failure (HF) and retard the progression of chronic kidney disease (CKD) in patients with type 2 diabetes ...
Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshima, Hisayuki Katsuyama   +3 more
doaj   +1 more source

Endothelial dysfunction assessed by brachial artery flow-mediated dilatation predicts severe COVID-19-related disease

Journal of Family Medicine and Primary Care, 2022
Background: Endothelial dysfunction, inflammation, and hypercoagulability are hallmarks of severe COVID-19 related disease. Endothelial function can be measured non-invasively by flow-mediated dilatation in the brachial artery.
Rohit Walia, Venkat Subaih Arunachalam, Udit Chauhan, Meenakshi Khapre, Poonam Arora   +4 more
doaj   +1 more source

Exercise Improves Endothelial Function via the lncRNA MALAT1/miR-320a Axis in Obese Children and Adolescents

Cardiology Research and Practice, 2021
Background. Endothelial dysfunction commonly occurs in obese children and adolescents, leading to an increased risk of cardiovascular diseases. Exercise has significant protective effects against endothelial dysfunction through regulating some noncoding ...
Wei Zhao, Yane Yin, Huiling Cao, Yandong Wang   +3 more
doaj   +1 more source

miR-205-5p inhibits homocysteine-induced pulmonary microvascular endothelium dysfunction by targeting FOXO1

Acta Biochimica et Biophysica Sinica, 2023
Homocysteine (Hcy) is a risk factor for multiple chronic diseases, and vascular endothelial cell injury has been regarded as the initiating step for this process.
Huang Xiaobo, Li Zhen, Zhang Ling, Yang Yali, Wang Yanjia, Li Sirui, Li Guizhong, Feng Huiping, Yang Xiaoling   +8 more
doaj   +1 more source

The association between endothelial dysfunction and subclinical myocardial injury in male obstructive sleep apnoea patients

ERJ Open Research
Background Endothelial dysfunction was shown to contribute significantly to the elevated cardiovascular risk observed in the general population. However, the relationship between endothelial dysfunction and subclinical myocardial injury in obstructive ...
Wenhao Cao, Jinmei Luo, Xinjie Hui, Yi Xiao, Rong Huang   +4 more
doaj   +1 more source