Results 21 to 30 of about 1,223,204 (255)
Biomedicines, 2021 The CR6-interacting factor1 (CRIF1) mitochondrial protein is indispensable for peptide synthesis and oxidative phosphorylation. Cardiomyocyte-specific deletion of CRIF1 showed impaired mitochondrial function and cardiomyopathy.
Shuyu Piao +7 more
doaj +1 more source
Rethinking Endothelial Dysfunction as a Crucial Target in Fighting Heart Failure
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019 Endothelial dysfunction is characterized by nitric oxide dysregulation and an altered redox state. Oxidative stress and inflammatory markers prevail, thus promoting atherogenesis and hypertension, important risk factors for the development and ...
Courtney Premer, PhD +3 more
doaj +1 more source
Clinical and Experimental Dental Research, 2020 The present study aimed to assess the relationship between periodontal condition and endothelial function using a noninvasive device. Many recent studies have reported associations between periodontitis and cardiovascular diseases.
Takahito Fujitani +3 more
doaj +1 more source
Mechanisms and Clinical Implications of Endothelial Dysfunction in Arterial Hypertension
Journal of Cardiovascular Development and Disease, 2022 The endothelium is composed of a monolayer of endothelial cells, lining the interior surface of blood and lymphatic vessels. Endothelial cells display important homeostatic functions, since they are able to respond to humoral and hemodynamic stimuli ...
Pasquale Ambrosino +9 more
doaj +1 more source
Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]
, 2003 Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Keaney, John F. +5 more
core +1 more source
Atrial Natriuretic Peptide Protects against Histamine-Induced Endothelial Barrier Dysfunction in Vivo [PDF]
, 2008 Endothelial barrier dysfunction is a hallmark of many severe pathologies, including sepsis or atherosclerosis. The cardiovascular hormone atrial natriuretic peptide (ANP) has increasingly been suggested to counteract endothelial leakage.
Mayer, Bettina A. +9 more
core +1 more source
Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase [PDF]
, 2009 Proline-rich tyrosine kinase 2 (PYK2) can be activated by angiotensin II (Ang II) and reactive oxygen species. We report that in endothelial cells, Ang II enhances the tyrosine phosphorylation of endothelial NO synthase (eNOS) in an AT1-, H2O2-, and PYK2-
Loot, Annemarieke E. +7 more
core +1 more source
INSULIN RESISTANCE AND ENDOTHELIAL DYSFUNCTION IN RHEUMATOID ARTHRITIS [PDF]
Romanian Journal of Rheumatology, 2016 Rheumatoid arthritis is a chronic inflammatory disease, in which, besides articular involvement, cardiovascular complications due to premature and accelerated atherosclerosis represent a serious problem.
Alexandru Caraba +3 more
doaj +1 more source
Experimental models for vascular endothelial dysfunction
Bangladesh Journal of Pharmacology, 2021 Vascular endothelial dysfunction is characterized by apoptosis of endothelial cells, an imbalance between vasoconstrictory and vasodilatory substances, the imbalance between ROS and antioxidants, vascular remodeling, loss of vascular integrity which ...
Anchal Garg +3 more
doaj +1 more source
Treatment of periodontitis and endothelial function [PDF]
, 2007 Background: Systemic inflammation may impair vascular function, and epidemiologic data suggest a possible link between periodontitis and cardiovascular disease.
Deanfield, John +19 more
core +1 more source