Results 11 to 20 of about 399,722 (264)
Rethinking Endothelial Dysfunction as a Crucial Target in Fighting Heart Failure
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019 Endothelial dysfunction is characterized by nitric oxide dysregulation and an altered redox state. Oxidative stress and inflammatory markers prevail, thus promoting atherogenesis and hypertension, important risk factors for the development and ...
Courtney Premer, PhD +3 more
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Clinical and Experimental Dental Research, 2020 The present study aimed to assess the relationship between periodontal condition and endothelial function using a noninvasive device. Many recent studies have reported associations between periodontitis and cardiovascular diseases.
Takahito Fujitani +3 more
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Biomedicines, 2021 The CR6-interacting factor1 (CRIF1) mitochondrial protein is indispensable for peptide synthesis and oxidative phosphorylation. Cardiomyocyte-specific deletion of CRIF1 showed impaired mitochondrial function and cardiomyopathy.
Shuyu Piao +7 more
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Mechanisms and Clinical Implications of Endothelial Dysfunction in Arterial Hypertension
Journal of Cardiovascular Development and Disease, 2022 The endothelium is composed of a monolayer of endothelial cells, lining the interior surface of blood and lymphatic vessels. Endothelial cells display important homeostatic functions, since they are able to respond to humoral and hemodynamic stimuli ...
Pasquale Ambrosino +9 more
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Endothelial dysfunction and atherosclerosis [PDF]
European Heart Journal, 1997 Mammalian endothelium acts as a mediator in arterial and venous relaxation and contraction. Endothelium-dependent relaxation is due to endothelial release of powerful, non-prostanoid vasodilatory substances. The best known of these is the endothelial factor EDRF identified as nitrous oxide (NO).
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Endothelial Dysfunction in Diabetes [PDF]
Biomedicines, 2020 Diabetes is a worldwide health issue closely associated with cardiovascular events. Given the pandemic of obesity, the identification of the basic underpinnings of vascular disease is strongly needed. Emerging evidence has suggested that endothelial dysfunction is a critical step in the progression of atherosclerosis.
Yusuke Takeda +6 more
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INSULIN RESISTANCE AND ENDOTHELIAL DYSFUNCTION IN RHEUMATOID ARTHRITIS [PDF]
Romanian Journal of Rheumatology, 2016 Rheumatoid arthritis is a chronic inflammatory disease, in which, besides articular involvement, cardiovascular complications due to premature and accelerated atherosclerosis represent a serious problem.
Alexandru Caraba +3 more
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Endothelial dysfunction in diabetes [PDF]
British Journal of Pharmacology, 2000 Endothelial dysfunction plays a key role in the pathogenesis of diabetic vascular disease. The endothelium controls the tone of the underlying vascular smooth muscle through the production of vasodilator mediators. The endothelium‐derived relaxing factors (EDRF) comprise nitric oxide (NO), prostacyclin, and a still elusive endothelium‐derived ...
De Vriese, AS +4 more
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Experimental models for vascular endothelial dysfunction
Bangladesh Journal of Pharmacology, 2021 Vascular endothelial dysfunction is characterized by apoptosis of endothelial cells, an imbalance between vasoconstrictory and vasodilatory substances, the imbalance between ROS and antioxidants, vascular remodeling, loss of vascular integrity which ...
Anchal Garg +3 more
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Hyperhomocysteinemia and Endothelial Dysfunction [PDF]
Current Hypertension Reviews, 2009 Hyperhomocysteinemia (HHcy) is a significant and independent risk factor for cardiovascular diseases. Endothelial dysfunction (ED) is the earliest indicator of atherosclerosis and vascular diseases. We and others have shown that HHcy induced ED in human and in animal models of HHcy induced by either high-methionine load or genetic deficiency.
Zhongjian, Cheng +2 more
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