Results 11 to 20 of about 635,820 (301)

Bubble-Induced Endothelial Microparticles Promote Endothelial Dysfunction. [PDF]

PLoS ONE, 2017
Decompression sickness is a systemic pathophysiological process caused by bubbles and endothelial microparticles (EMPs) are established markers reflecting competency of endothelial function and vascular biology.
Xuhua Yu, Jiajun Xu, Guoyang Huang, Kun Zhang, Long Qing, Wenwu Liu, Weigang Xu   +6 more
doaj   +1 more source

Rethinking Endothelial Dysfunction as a Crucial Target in Fighting Heart Failure

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019
Endothelial dysfunction is characterized by nitric oxide dysregulation and an altered redox state. Oxidative stress and inflammatory markers prevail, thus promoting atherogenesis and hypertension, important risk factors for the development and ...
Courtney Premer, PhD, Anthony J. Kanelidis, MD, Joshua M. Hare, MD, Ivonne Hernandez Schulman, MD   +3 more
doaj   +1 more source

Association between periodontitis and vascular endothelial function using noninvasive medical device—A pilot study

Clinical and Experimental Dental Research, 2020
The present study aimed to assess the relationship between periodontal condition and endothelial function using a noninvasive device. Many recent studies have reported associations between periodontitis and cardiovascular diseases.
Takahito Fujitani, Norio Aoyama, Fumihiko Hirata, Masato Minabe   +3 more
doaj   +1 more source

SIRT1 Activation Attenuates the Cardiac Dysfunction Induced by Endothelial Cell-Specific Deletion of CRIF1

Biomedicines, 2021
The CR6-interacting factor1 (CRIF1) mitochondrial protein is indispensable for peptide synthesis and oxidative phosphorylation. Cardiomyocyte-specific deletion of CRIF1 showed impaired mitochondrial function and cardiomyopathy.
Shuyu Piao, Ikjun Lee, Seon-Ah Jin, Seonhee Kim, Harsha Nagar, Su-jeong Choi, Byeong Hwa Jeon, Cuk-Seong Kim   +7 more
doaj   +1 more source

Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module. [PDF]

, 2019
Blood vessels in the CNS form a specialized and critical structure, the blood-brain barrier (BBB). We present a resource to understand the molecular mechanisms that regulate BBB function in health and dysfunction during disease.
Aydin, Sidar, Batugal, Austin, Cabangcala, Anne Christelle, Daneman, Richard, Gimlin, Kayleen, Hashimoto, Tomoki, Korai, Masaaki, Kotoda, Masakazu, Munji, Roeben Nocon, Noble-Haeusslein, Linda J, Oldham, Michael Clark, Schupp, Patrick Georg, Semple, Bridgette Deanne, Sohet, Fabien, Soung, Allison Luen, Trivedi, Alpa, Weiner, Geoffrey Aaron   +16 more
core   +1 more source

Mechanisms and Clinical Implications of Endothelial Dysfunction in Arterial Hypertension

Journal of Cardiovascular Development and Disease, 2022
The endothelium is composed of a monolayer of endothelial cells, lining the interior surface of blood and lymphatic vessels. Endothelial cells display important homeostatic functions, since they are able to respond to humoral and hemodynamic stimuli ...
Pasquale Ambrosino, Tiziana Bachetti, Silvestro Ennio D’Anna, Brurya Galloway, Andrea Bianco, Vito D’Agnano, Antimo Papa, Andrea Motta, Fabio Perrotta, Mauro Maniscalco   +9 more
doaj   +1 more source

The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD [PDF]

, 2016
Objective The balance between coronary endothelial dysfunction and repair is influenced by many protective and deleterious factors circulating in the blood.
Ahmed, Nadeem, Berry, Colin, Hayhurst, James, Kennedy, Simon, McClure, John D., Oldroyd, Keith G., Wadsworth, Roger M., Watt, Jonathan   +7 more
core   +1 more source

Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]

, 2018
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura, D’Amato, Andrea, Fedele, Francesco, Mancone, Massimo, Netti, Lucrezia, Palmirotta, Raffaele, Pucci, Mariateresa, Severino, Paolo, Volterrani, Maurizio   +8 more
core   +11 more sources

Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy. [PDF]

, 2009
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Abhiram Prasad, Amir Lerman, Anderson, Barter, Blake, Bonetti, Cannon, Chait, Charanjit S. Rihal, Colhoun, Cromwell, Deanfield, El Harchaoui, Ford, Forrest, Gurpreet S. Sandhu, Hartman, Hermann, Jeyarajah, Johansson, Joseph P. McConnell, Kathiresan, Kuller, Kuller, Lavi, Lavi, Lerman, Lilach O. Lerman, Mackey, Mackey, Monique A. Ford, Mora, Mora, Otvos, Rosenson, Shahar Lavi, Sirtori, Stacy J. Hartman, Suwaidi, Vakkilainen, van der Steeg, Vergeer, Woodman   +42 more
core   +1 more source

Endothelial dysfunction and atherosclerosis [PDF]

European Heart Journal, 1997
Mammalian endothelium acts as a mediator in arterial and venous relaxation and contraction. Endothelium-dependent relaxation is due to endothelial release of powerful, non-prostanoid vasodilatory substances. The best known of these is the endothelial factor EDRF identified as nitrous oxide (NO).
openaire   +5 more sources