Results 11 to 20 of about 403,263 (261)

Endothelial dysfunction reversibility [PDF]

open access: yesVojnosanitetski Pregled, 2007
Coronary artery disease, the leading cause of morbidity and mortality, is a continuum of events that can lead to end stage heart disease . Common to the pathogenesis of most cardiovascular diseases are the processes, called risk factors for atherosclerotic coronary artery disease, that cause pathologic change and dysfunction in the blood vessels and ...
Obrenović-Kirćanski Biljana B.
doaj   +3 more sources

Endothelial Dysfunction [PDF]

open access: yesJournal of the American Society of Nephrology, 2004
Endothelial dysfunction is characterized by a shift of the actions of the endothelium toward reduced vasodilation, a proinflammatory state, and prothrombic properties. It is associated with most forms of cardiovascular disease, such as hypertension, coronary artery disease, chronic heart failure, peripheral artery disease, diabetes, and chronic renal ...
Dierk H, Endemann, Ernesto L, Schiffrin
openaire   +2 more sources

Mechanisms and Clinical Implications of Endothelial Dysfunction in Arterial Hypertension

open access: yesJournal of Cardiovascular Development and Disease, 2022
The endothelium is composed of a monolayer of endothelial cells, lining the interior surface of blood and lymphatic vessels. Endothelial cells display important homeostatic functions, since they are able to respond to humoral and hemodynamic stimuli ...
Pasquale Ambrosino   +9 more
doaj   +1 more source

Endothelial dysfunction and atherosclerosis [PDF]

open access: yesEuropean Heart Journal, 1997
Mammalian endothelium acts as a mediator in arterial and venous relaxation and contraction. Endothelium-dependent relaxation is due to endothelial release of powerful, non-prostanoid vasodilatory substances. The best known of these is the endothelial factor EDRF identified as nitrous oxide (NO).
openaire   +5 more sources

INSULIN RESISTANCE AND ENDOTHELIAL DYSFUNCTION IN RHEUMATOID ARTHRITIS [PDF]

open access: yesRomanian Journal of Rheumatology, 2016
Rheumatoid arthritis is a chronic inflammatory disease, in which, besides articular involvement, cardiovascular complications due to premature and accelerated atherosclerosis represent a serious problem.
Alexandru Caraba   +3 more
doaj   +1 more source

Endothelial dysfunction in diabetes [PDF]

open access: yesBritish Journal of Pharmacology, 2000
Endothelial dysfunction plays a key role in the pathogenesis of diabetic vascular disease. The endothelium controls the tone of the underlying vascular smooth muscle through the production of vasodilator mediators. The endothelium‐derived relaxing factors (EDRF) comprise nitric oxide (NO), prostacyclin, and a still elusive endothelium‐derived ...
De Vriese, AS   +4 more
openaire   +4 more sources

Experimental models for vascular endothelial dysfunction

open access: yesBangladesh Journal of Pharmacology, 2021
Vascular endothelial dysfunction is characterized by apoptosis of endothelial cells, an imbalance between vasoconstrictory and vasodilatory substances, the imbalance between ROS and antioxidants, vascular remodeling, loss of vascular integrity which ...
Anchal Garg   +3 more
doaj   +1 more source

Hyperhomocysteinemia and Endothelial Dysfunction [PDF]

open access: yesCurrent Hypertension Reviews, 2009
Hyperhomocysteinemia (HHcy) is a significant and independent risk factor for cardiovascular diseases. Endothelial dysfunction (ED) is the earliest indicator of atherosclerosis and vascular diseases. We and others have shown that HHcy induced ED in human and in animal models of HHcy induced by either high-methionine load or genetic deficiency.
Zhongjian, Cheng   +2 more
openaire   +2 more sources

Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification

open access: yesScientific Reports, 2018
Endothelial dysfunction contributes to sepsis outcome. Metabolic phenotypes associated with endothelial dysfunction are not well characterised in part due to difficulties in assessing endothelial metabolism in situ.
Sarah McGarrity   +8 more
doaj   +1 more source

Endothelial Function in Dyslipidemia: Roles of LDL-Cholesterol, HDL-Cholesterol and Triglycerides

open access: yesCells, 2023
Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial step for atherosclerosis, resulting in cardiovascular complications.
Yukihito Higashi
doaj   +1 more source

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