Results 121 to 130 of about 125,744 (212)
In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 3, Page 838-852, March 2026.ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini +5 more
wiley +1 more source
Artificial intelligence-driven metabolomics of retinal nerve fibre layer to profile risks of mortality and cardiometabolic diseases. [PDF]
Nat CommunYang S +13 more
europepmc +1 more source
2020 8th International Conference on Condition Monitoring and Diagnosis (CMD), 2020 openaire +1 more source
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides
Journal of Peptide Science, Volume 32, Issue 3, March 2026.As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama +2 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2061-2074, March 2026.Abstract Aims To evaluate the accuracy of abdominal fat distribution of subcutaneous (SAT) and visceral adipose tissue (VAT) assessed by ultrasound (US) compared to magnetic resonance imaging (MRI), as the gold standard technique. Additionally, to assess the association between abdominal fat distribution measured by US and metabolic conditions in ...
Claudia Jiménez‐ten Hoevel +6 more
wiley +1 more source
Wireless Movement Activity and Cardiometabolic Disease Risk in Historical Redlined Areas. [PDF]
JACC AdvZhang T +7 more
europepmc +1 more source
Plant, Cell &Environment, Volume 49, Issue 3, Page 1491-1504, March 2026.ABSTRACT Cell wall–degrading enzymes are viewed as extracellular virulence factors. However, their potential to act as immune elicitors and interact with intracellular immune receptors remains poorly defined. Here, we demonstrate that six conserved glycoside hydrolase 7 (GH7) family proteins from the fungal pathogen Verticillium dahliae have dual roles
Xiao‐Bin Ji +10 more
wiley +1 more source
Associations of asthma with cardiometabolic diseases and multimorbidity: A cohort study in the UK Biobank. [PDF]
NPJ Prim Care Respir MedLin J +6 more
europepmc +1 more source
Angewandte Chemie, Volume 138, Issue 7, 9 February 2026.Ni: neue Lösung für asymmetrische C(sp3)‐H‐Aktivierung. Die stereoselektive Synthese vollständig kohlenstoffsubstituierter quartärer Stereozentren gelingt durch eine enantioselektive C(sp3)‐H‐Arylierung unter Verwendung eines Ni‐Katalysators auf der Basis eines BINOL‐Derivaten.
Erwan Brunard +4 more
wiley +1 more source