Results 161 to 170 of about 127,621 (244)

The Future of the Obesity Management Landscape: Challenges, Opportunities and Solutions

open access: yesObesity Science &Practice, Volume 12, Issue 2, April 2026.
ABSTRACT Objective In July 2023 a diverse group of international experts from academia, healthcare and medical technology/pharmacological companies gathered to discuss the current global landscape in the management of obesity, identify the clinical challenges healthcare systems are facing, and the gaps in scientific knowledge. Approach We proposed ways
Alexander Dimitri Miras   +23 more
wiley   +1 more source

Understanding cell‐penetrating peptide mechanisms using computational electrophysiology simulations

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Cell‐penetrating peptides (CPPs) can enter cells without inducing cytotoxicity and can be coupled with cargo molecules to be used to deliver drugs, DNA, or nanoparticles into cells. The peptide‐membrane interactions driving the internalization mechanism are not completely understood. In this study, we introduce Computational Electrophysiology (
Eric Catalina‐Hernandez   +3 more
wiley   +1 more source

The Kinetic Consequences of Water on Catalytic Methane Pyrolysis. [PDF]

open access: yesACS Catal
Nguyen PT   +7 more
europepmc   +1 more source

Vegetal residue‐based formulation of Trichoderma ossianense, a new indigenous vineyard species adapted to alkaline pH with potential biocontrol ability against Black‐foot disease pathogens

open access: yesPest Management Science, Volume 82, Issue 4, Page 2910-2924, April 2026.
The study identifies Trichoderma ossianense, was can be isolated from grapevine roots, is capable of growing at alkaline pH and controls black‐foot pathogens, highlighting the vegetal residue‐based formulations that preserve its viability. Abstract BACKGROUND Fungi of the Trichoderma genus are used in vineyards as biological control agents mainly ...
Laura Zanfaño   +7 more
wiley   +1 more source

The use of different types of networks, alone and in combination, for drug target identification

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 8, Page 1653-1662, April 2026.
Current therapeutic approaches often focus on targeting clinical symptoms or peripheral phenotypes rather than the underlying molecular mechanisms, or endophenotypes, that drive diseases. While symptom‐based drugs can alleviate discomfort, they do not necessarily alter disease progression and may overlook opportunities for prevention or early ...
Paolo Parini
wiley   +1 more source

What Goes First? Effects of Starvation on the Body Condition of a Neotropical Dung Beetle

open access: yesEntomologia Experimentalis et Applicata, Volume 174, Issue 4, Page 321-328, April 2026.
We investigated how prolonged starvation affects key physiological traits in the dung beetle Dichotomius bos. Prolonged starvation leads to significant reductions in body dry mass and fat reserves, while muscle mass remains unchanged. These findings indicate that dung beetles prioritize the maintenance of locomotor muscles while mobilizing stored ...
Leonardo Vilas‐Bôas M. P. de Cerqueira   +5 more
wiley   +1 more source

CardioMetAge estimates cardiometabolic aging and predicts disease outcomes. [PDF]

open access: yesBMC Med
Li Y   +11 more
europepmc   +1 more source

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