The Journal of Physiology, EarlyView.Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray +16 more
wiley +1 more source
Diagnostic performance of exercise stress testing findings and coronary microvascular dysfunction in patients with angina with non-obstructive coronary artery disease. [PDF]
HeartTsai TY +17 more
europepmc +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Incremental Prognostic Power of Coronary Flow Reserve and Artificial Intelligence-Enabled ECG-Derived Filling Pressure in Angina With Nonobstructive Coronary Arteries. [PDF]
J Am Heart AssocKalhor P +7 more
europepmc +1 more source
Circular RNAs: Unlocking new avenues in cardiometabolic disease management
The Journal of Physiology, EarlyView.Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor +4 more
wiley +1 more source
A cross-sectional study on the prevalence of cardiometabolic diseases and their multilevel socioeconomic impacts in Qianxinan Buyi and Miao Autonomous Prefecture, Southwest China. [PDF]
Medicine (Baltimore)Wu L, Long Y, Zou X, Ren L, Fang K.
europepmc +1 more source
Canadian Journal of Administrative Sciences / Revue Canadienne des Sciences de l'Administration, Volume 43, Issue 3, September 2026.ABSTRACT First Nations in Canada are exercising inherent sovereignty through cannabis entrepreneurship, enacting community‐based regulatory frameworks and asserting jurisdictional authority over economic activities within their territories. Through analyzing 71 Canadian media articles, this study examines how First Nations governance innovation and ...
Tamara Donnelly, Iliana Loupessis
wiley +1 more source
Coronary Microvascular Dysfunction and Lipid Molecules: Pathophysiological Mechanisms, Clinical Assessment, and Therapeutic Implications. [PDF]
J Pers MedHafez A +14 more
europepmc +1 more source
Thermal Stress Is Associated With Fragmentation of Mediterranean Posidonia oceanica Meadows
Global Change Biology Communications, Volume 1, Issue 3, September 2026.By combining a physiological model of cumulative thermal stress with AI‐based seagrass mapping, we show that chronic sublethal warming is associated with fragmentation of Mediterranean Posidonia oceanica meadows and increased regression risk by 2100. ABSTRACT Posidonia oceanica meadows, which underpin Mediterranean coastal ecosystems, are undergoing ...
Àlex Giménez‐Romero +3 more
wiley +1 more source
Myocardial Infarction With Nonobstructive Coronary Arteries With Coronary Microvascular Dysfunction Associated With Systemic Sclerosis: Case Report. [PDF]
Case Rep Vasc MedOhga Y +15 more
europepmc +1 more source