Results 41 to 50 of about 43,496 (243)

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Weather Attention in Online Discourse and Price Uncertainty in Agricultural Futures Markets

Agribusiness, EarlyView.
ABSTRACT Weather is a central determinant of production risk in agricultural markets, but markets respond not only to weather conditions themselves, but also to how those conditions are noticed, framed, and interpreted in public discourse. In this setting, real‐time online weather discussions may shape price uncertainty by influencing how market ...
Mario A. Ortez, Olga Isengildina Massa, Michael Liam Smith, Nicole Olynk Widmar   +3 more
wiley   +1 more source

Thermo-oxidative crosslinking of carbon fiber reinforced PEEK (Polyetheretherketone) for additive manufactured ceramic matrix composites

Advanced Manufacturing: Polymer & Composites Science
Carbon fiber reinforced polyetheretherketone (CF-PEEK) samples were fabricated using material extrusion. These additive manufactured green bodies are later processed to their final application as ceramic matrix composites (CMC) by the liquid silicon ...
Wolfgang Freudenberg, Felix Wich, Jalena Best, Elena Moukhina, Tim Scherzer, Holger Ruckdäschel, Nico Langhof, Stefan Schafföner   +7 more
doaj   +1 more source

Optimal Indication of D3 Lymph Node Dissection for Non‐Metastatic Colon Cancers by Tumor Stages: Evaluation of Therapeutic Value Index for Each Lymph Node Station

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aims To explore the therapeutic impact of D3 lymph node dissection for non‐metastatic colon cancers, evaluating the therapeutic value index for each lymph node station according to surgical stages. Methods Consecutive patients with surgical Stage I–III colon and rectosigmoid cancer who underwent curative resection between January 2003 and ...
Akira Ouchi, Kozo Kataoka, Eiji Shinto, Takashi Akiyoshi, Takefumi Yoshida, Yasuyuki Takamizawa, Yukihide Kanemitsu, Hirotoshi Kobayashi, Hideki Ueno, on behalf of the Lymph Nodes Committee of JSCCR   +9 more
wiley   +1 more source

Multi-scale image preprocessing and feature tracking for remote CME characterization

Journal of Space Weather and Space Climate, 2022
Coronal Mass Ejections (CMEs) influence the interplanetary environment over vast distances in the solar system by injecting huge clouds of fast solar plasma and energetic particles (SEPs).
Stepanyuk Oleg, Kozarev Kamen, Nedal Mohamed   +2 more
doaj   +1 more source

Transient anterior chamber intraocular lens opacification by triamcinolone acetonide following intravitreal injection

GMS Ophthalmology Cases
Background: Pseudophakic cystoid macular edema (CME) following primary anterior-chamber intraocular lens (ACIOL) implantations is commonly seen. Intravitreal triamcinolone acetonide (IVTA) injections have shown significant improvement in visual acuity ...
Kumar, Kshitiz, Agarwal, Deepak, Bajaj, Aditya, Saha, Subrata   +3 more
doaj   +1 more source

Experiences from Two Ways of Integrating Pre- and Post-course Multiple-choice Assessment Questions in Educational Events for Surgeons

Journal of European CME, 2021
To examine how to optimise the integration of multiple-choice questions (MCQs) for learning in continuing professional development (CPD) events in surgery, we implemented and evaluated two methods in two subspecialities over multiple years.
Monica Ghidinelli, Michael Cunningham, Isobel C. Monotti, Nishma Hindocha, Alain Rickli, Iain McVicar, Mark Glyde   +6 more
doaj   +1 more source

Katalytischer Schwefelatomtransfer vermittelt durch einen Bis(disulfido)‐Titankomplex

Angewandte Chemie, EarlyView.
Mehrelektronentransformationen mit Titan sind aufgrund der limitierten Zugänglichkeit niedervalenter Vorstufen bislang nur unzureichend untersucht. Die Vier‐Elektronen‐Aktivierung von elementarem Schwefel durch einen Ti(IV)‐Komplex führt zu einem seltenen Bis(disulfido)‐Titankomplex, der die effiziente katalytische Synthese von Isothiocyanaten aus ...
Sebastian Samir Cremer, Peter Coburger, Corinna Czernetzki, Gabriele Hierlmeier   +3 more
wiley   +1 more source

Virtual patient simulation platforms challenging traditional CME: Identification of gaps in knowledge in the management of Type 2 diabetes and Hyperlipidaemia

Journal of European CME, 2021
As any other aspect of contemporary life, an old and established field of CME undergoes a transformation into a “digital age.” Virtual patient simulation (VPS) has shown to be an interactive and efficient way of engaging healthcare professionals (HCP) in
Igal Iancu, Eugene Pozniak, Boris Draznin   +2 more
doaj   +1 more source

CONTINUING MEDICAL EDUCATION (CME): A BASIS FOR QUALITY IMPROVEMENT OF HEALTH SERVICES [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2000
According to the modern management, quality is defined from the view of customers. In health services, quality improvement requires appropriate measures to increase responsiveness and accountability of health system to increasing demands of the ...
Ali reza Yousefi, Abbas Rezaie
doaj