Results 61 to 70 of about 61,154 (291)

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source

Disseminated Mycobacterium abscessus infection with idiopathic CD4+ T-lymphocytopenia: a case report and review of the literature

Journal of Medical Case Reports
Background Idiopathic CD4+ T lymphocytopenia is a rare immune dysfunction disease that is usually found after opportunistic infections. Mycobacterium abscessus is a rapidly growing mycobacterium that can cause pulmonary infections, lymphadenitis, skin ...
Xianglin Wu, Mingzhu Zhai, Aohong Xu, Yi Zheng   +3 more
doaj   +1 more source

integração nacional e fragmentação regional da indústria de transformação: Sudeste e Nordeste

Revista Economia Política do Desenvolvimento, 2010
O artigo faz uma análise do processo de (des)concentração industrial que ocorreu no Brasil, com enfoque nas transformações do Sudeste e Nordeste a partir dos anos 60 e 70 do século XX.
LÍVIO ANDRADE WANDERLEY
doaj   +1 more source

Characterization of CME-driven shock in the interplanetary medium using type II radio bursts [PDF]

, 2017
Type II radio bursts are indirect signatures of the fast magnetosonic shock formation in the heliosphere. Those types of MHD shocks accelerate electron beams that via plasma emission mechanism produce electromagnetic radiation.
Diaz Castillo, Saida Milena
core  

From Nonfinancial Reporting to Management Control: A GRI‐Based Sustainability Balanced Scorecard

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The integration of sustainability into strategic management systems has shifted from a reporting‐oriented exercise to a challenge of implementation, control, and accountability. Although the SBSC is widely acknowledged as a suitable framework to embed environmental and social objectives into strategy execution, its practical application ...
Piedad Ortiz‐Fernández, Belén Payán‐Sánchez, Eva Carmona‐Moreno   +2 more
wiley   +1 more source

The spheroid CME model in EUHFORIA [PDF]

Predictions of coronal mass ejection (CME) propagation and impact in the heliosphere, in either research or operational settings, are usually performed by employing magnetohydrodynamic (MHD) models.
Palmerio Erika, Scolini Camilla
core   +2 more sources

Impact of participation in continuing medical education small group learning (CME-SGL) on the stress, morale, and professional isolation of rurally-based GPs: a qualitative study in Ireland

BJGP Open, 2019
Background: The pressures of general practice contribute to high levels of stress, low morale, and burnout in some GPs. In addition, rurally-based doctors may experience significant professional isolation.
Stephanie Dowling, Jason Last, Henry Finnegan, Pat Daly, John Bourke, Conor Hanrahan, Pat Harrold, Geoff McCombe, Walter Cullen   +8 more
doaj   +1 more source

Condições de trabalho e fatores de risco à saúde dos trabalhadores do Centro de material Esterilizado do Hospital de Clínicas da UFPR [PDF]

, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.O presente estudo teve por objetivo principal contribuir para a melhoria das condições de trabalho no Centro de ...
Castro, Maria Edutania Skroski
core  

Photospheric signatures of CME onset [PDF]

Coronal mass ejections (CMEs) are solar eruptions that involve large-scale changes to the magnetic topology of an active region. There exists a range of models for CME onset which are based on twisted or sheared magnetic field above a polarity inversion ...
Romano, P., Fletcher, L, Aslam, O.P.M., MacTaggart, D, Mactaggart, D., Aslam, O P M, Williams, T., Fletcher, L., Romano, P, Williams, T   +9 more
core   +1 more source

Intersecting Structures and Gendered Perceptions in Entrepreneurship: A Life‐Course Comparison of Institutional Inclusivity in Italy and the United Kingdom

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Using Global Entrepreneurship Monitor (GEM) 2024 data for Italy and the United Kingdom, this study examines how gender gaps in entrepreneurial perceptions, measured as perceived entrepreneurial skills and fear of failure, vary across age and education within contrasting institutional regimes.
Giusy Sica, Chiara Spiniello, Maria Palazzo, Alessandra Micozzi, Giovanna Truda   +4 more
wiley   +1 more source