Results 71 to 80 of about 4,777 (186)

Circulating Sex Hormone Levels and Survival in Men With Esophageal Squamous Cell Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Men with esophageal squamous cell carcinoma (ESCC) have worse survival than women, a disparity in which sex hormones may play a role. Yet, whether circulating sex hormone levels are associated with survival in ESCC remains largely unexplored.
Zhiqiang Liu   +7 more
wiley   +1 more source

细胞角蛋白19片段抗原21-1含量化学发光微粒子定量免疫检测方法的建立 [PDF]

open access: yes, 2018
目的建立细胞角蛋白19片段抗原21-1(cytokeratin 19 fragment 21-1,CYFRA21-1,简称CY21-1)含量的化学发光微粒子免疫检测方法(chemiluminescent microparticle immunoassay,CMIA)。方法原核表达制备重组CY21-1(r CY21-1),用其免疫BALB/c小鼠后,收集小鼠脾脏细胞,常规杂交瘤技术与Sp2/0进行融合,制备CY21-1单抗。间接ELISA法筛选可稳定分泌CY21-1抗体的杂交瘤细胞,分别标记微性磁珠 ...
郭小怡   +5 more
core   +1 more source

Improving Linkage to the HCV Care Cascade in Nonspecialist Settings: Evaluation of the Performance and Triage Utility of the Elecsys HCV Duo Assay in Japan

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 15, August 2026.
In nonspecialist departments, most anti‐HCV–positive individuals do not proceed to RNA testing. The Elecsys HCV Duo assay simultaneously detects anti‐HCV antibodies and core antigen from a single blood draw and preferentially identifies patients with clinically meaningful viral loads.
Hiroko Setoyama   +23 more
wiley   +1 more source

Changes of CEA Diagnostic Performance Under the New Reference Interval Stratified by Age and Sex

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.
Our study included patients with lung cancer, breast cancer, and colorectal cancer and apparently healthy individuals, conducted a large case–control study to assess the effects of age and sex on serum concentrations and positive rates of CEA, established age‐ and sex‐stratified reference intervals using indirect methods.
Ke Zhang, Xiarui Ye
wiley   +1 more source

Comparison of LC-MS/MS and chemiluminescent immunoassays for immunosuppressive drugs reveals organ dependent variation in blood cyclosporine a concentrations [PDF]

open access: yes, 2020
Introduction: Life-long monitoring of immunosuppressive drugs (ISDs) in blood is essential after organ transplantation. However, the ISD concentrations vary depending on the assay employed.
Becker, Anna   +2 more
core   +1 more source

The differential impacts of COVID-19 mortality on mental health by residential geographic regions: The Los Angeles Pandemic Surveillance Cohort Study.

open access: yesPLoS ONE
ObjectiveThis study examines the association between changes in mental health before and during the COVID-19 pandemic and COVID-19 mortality across geographic areas and by race/ethnicity.MethodsA cross-sectional survey was conducted in Los Angeles County
Chun Nok Lam   +6 more
doaj   +1 more source

Sudomotor dysfunction in people with type 1 diabetes with and without clinical peripheral neuropathy: A study from Pune, India

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 8, Page 1358-1366, August 2026.
ABSTRACT Background and Aims It is appreciated that current screening tools for diabetic peripheral neuropathy (DPN) often fail to detect early disease. Sudomotor (sweat gland) dysfunction, among the earliest manifestations of DPN, can be measured objectively by the SUDOSCAN® device. We compared SUDOSCAN® with conventional validated screening (Michigan
Rohan Shah   +6 more
wiley   +1 more source

Screening of Syphilis Using the Reverse Algorithm and its Trends Among Healthy/Asymptomatic Blood Donors: A Regional Transfusion Centre Study from Northern Pakistan

open access: yesPakistan Armed Forces Medical Journal
Objective: To determine the syphilis trends by using the reverse algorithm in healthy/asymptomatic blood donors from Northern Pakistan. Study Design: Perspective longitudinal study.
Tahir Ghafoor   +5 more
doaj   +1 more source

Trends in Hepatitis B, Hepatitis C, and HIV Seroprevalence in the Netherlands: Insights From Two Decades of Nationwide PIENTER Serosurveys

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT Hepatitis B (HBV), hepatitis C (HCV), and HIV remain public health challenges despite effective treatments and preventive options. Infections are often asymptomatic, leading to undiagnosed cases, onward transmission, and preventable morbidity and mortality.
Christine G. J. I. van Straten   +7 more
wiley   +1 more source

Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

open access: yesAndrology, Volume 14, Issue 5, Page 1272-1281, July 2026.
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto   +12 more
wiley   +1 more source

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