Results 1 to 10 of about 260,973 (300)

Investigating factors associated with thyroid hormone measurements during pregnancy

European Thyroid Journal
Background: Accurate assessment of thyroid status is essential for maternal and fetal management during pregnancy. This study measured human chorionic gonadotropin (HCG), albumin, and thyroxine-binding globulin (TBG) levels during pregnancy to clarify ...
Miho Fukushita, Jaeduk Yoshimura Noh, Natsuko Watanabe, Kosuke Inoue, Ai Yoshihara, Masako Matsumoto, Nami Suzuki, Masahiro Ichikawa, Masakazu Koshibu, Rei Hirose, Tatsuya Iida, Toshino Suzuki, Kiminori Sugino, Koichi Ito   +13 more
doaj   +1 more source

An Overview of Biotin Interference Impact on Immunoassays

Cyprus Journal of Medical Sciences
The interference of high concentrations of biotin in patients’ serum with certain immunoassays can lead to inaccurately high or low test results, which may confuse physicians and contribute to misdi-agnosis and inappropriate treatment.
Alfatih Aboalbasher Yousif, Nagia Suliman Ahmed, Ebtehal Mohamed, Shiema Abdemagid, Omar Mustafa, Abdelmonem Mohamed, Alaa Ali, Ahmed Omer, Nafisa Hassan, Ahmed Al Barbary, Abdullah Said Alghazi, Yassir Hamadalnil   +11 more
doaj   +1 more source

Production of monoclonal antibody and development of an icELISA for the detection of paxilline in grain

Food and Agricultural Immunology
Paxilline (PAX) is a tremorgenic mycotoxin that is thought to be associated with various syndromes in animals. To facilitate the determination of this toxin, a hapten was chemically synthesized and then respectively conjugated to Bovine Thyroglobulin ...
Jiaxin Wang, Wenhua Shang, Shibei Shao, Jialin Zhang, Qiuyang Wu, Min He, Licai Ma, Jianzhong Shen, Zhanhui Wang, Kai Wen   +9 more
doaj   +1 more source

Europium Complex-Loaded Albumin Nanoparticles as Probes for Time-Resolved Luminescent Immunoassay

Biosensors
We report the first analytical application of albumin nanoparticles loaded with luminescent europium complexes for immunoassay development. These nanoparticles, synthesized via a desolvation method, exhibited a uniform spherical morphology with a ...
Zarina Galaeva, Maria Bochkova, Mikhail Rayev, Pavel Khramtsov   +3 more
doaj   +1 more source

Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease

Cell Reports Medicine
Summary: Accurate diagnosis of early Parkinson’s disease requires platforms suitable for detecting minute amounts of neuronally derived biomarkers in the massive protein excess of easily accessible biofluids such as blood.
Shijun Yan, Wenjing Zhang, Xinying Li, Suman Dutta, Andrew R. Castle, Yiming Liu, Anis Sahoo, Chor Lai Lam, Nicholas J.F. Gatford, Michele T. Hu, Chen-zhong Li, Cheng Jiang, Bowen Shu, George K. Tofaris   +13 more
doaj   +1 more source

Microfluidic preparation of size- and lamellarity-controlled liposomes using a static mixer and the advantage of a multilamellar structure in biosensing applications

Frontiers in Bioengineering and Biotechnology
BackgroundLiposomes are useful tools for amplifying signals in biosensing techniques, which are used to detect and analyze biological molecules. The goal of this study is to improve the sensitivity of immunosorbent assays by optimizing the self-assembled
Makoto Kiuchi, Shinji Takeoka, Shinji Takeoka, Keitaro Sou   +3 more
doaj   +1 more source

APHRODITE: A Compact Lab-on-Chip Biosensor for the Real-Time Analysis of Salivary Biomarkers in Space Missions

Biosensors
One of the main challenges to be faced in deep space missions is to protect the health and ensure the maximum efficiency of the crew by preparing methods of prevention and in situ diagnosis.
Lorenzo Nardi, Nithin Maipan Davis, Serena Sansolini, Thiago Baratto de Albuquerque, Mohcine Laarraj, Domenico Caputo, Giampiero de Cesare, Seyedeh Rojin Shariati Pour, Martina Zangheri, Donato Calabria, Massimo Guardigli, Michele Balsamo, Elisa Carrubba, Fabrizio Carubia, Marco Ceccarelli, Michele Ghiozzi, Liyana Popova, Andrea Tenaglia, Marino Crisconio, Alessandro Donati, Augusto Nascetti, Mara Mirasoli   +21 more
doaj   +1 more source

Use of Heterophilic Blocking Tubes in Suspected Heterophile Antibody Interference Among Pubertal Patients

Medicina
Background and Objectives: Today, immunoassay methods are still widely used in the analysis of hormone tests. Due to the properties of the reagents used in immunoassay analyses and components other than the measured analyte, deviations in clinical ...
Aysun Ekinci, Revsa Evin Canpolat Erkan, Ismail Yildiz, Naile Fevziye Misirlioglu, Hafize Uzun   +4 more
doaj   +1 more source

Immunoassay for the purpose of solving current issues associated with standardization of allergen preparations

Биопрепараты: Профилактика, диагностика, лечение, 2018
The present article describes principal problematic issues that refer to the standardization of allergen preparations. It is shown that at present domestic allergen preparations are being standardized by protein content in allergenic material, however ...
L. V. Nevskaya, S. F. Radunskaya, E. I. Lavrenchik, A. A. Movsesyants, V. K. Kapitanova, M. Yu. Korotkova   +5 more
doaj  

Inverted Pyramid Nanostructures Coupled with a Sandwich Immunoassay for SERS Biomarker Detection

Nanomaterials
Cancer diagnostics often faces challenges, such as invasiveness, high costs, and limited sensitivity for early detection, emphasizing the need for improved approaches.
Wen-Huei Chang, Shao-Quan Zhang, Zi-Yi Yang, Chun-Hung Lin   +3 more
doaj   +1 more source