European Journal of Haematology, EarlyView.ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley +1 more source
Investigating the Impact of Protein Supplementation from Different Sources on Advanced Glycation End Products in Older Adults in Singapore Following a Healthy Dietary Pattern. [PDF]
NutrientsTing M +5 more
europepmc +1 more source
A guide to transcriptional cyclin‐dependent kinases in cancer
The FEBS Journal, EarlyView.Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin +2 more
wiley +1 more source
Real-World Management of Chronic Myelogenous Leukemia in an Underserved Patient Cohort at a Los Angeles Safety-Net Health System: Tyrosine Kinase Inhibitor Treatment Patterns and Outcomes From 2015 to 2024. [PDF]
Cancer MedZheng D +4 more
europepmc +1 more source
International Journal of Dermatology, EarlyView.ABSTRACT We report a patient with chronic myeloid leukemia who developed giant cellulitis‐like Sweet syndrome with concurrent retiform petechiae and vasculitis‐like histopathological changes. This case highlights a potential diagnostic pitfall whereby Sweet syndrome may clinically and histologically mimic cutaneous vasculitis.
Kangjie R. Chua +2 more
wiley +1 more source
Meta-Analysis of Imatinib Resistance in Chronic Myeloid Leukemia due to BIM Gene Deletion and Single Nucleotide Polymorphisms Reveals Ethnic Variations in Prevalence. [PDF]
EJHaemBhattarai A +4 more
europepmc +1 more source
Impact of Heat Block Drying on Morphologic Preservation and Staining of Peripheral Blood Smears
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Morphologic evaluation of the peripheral blood smear is critical for diagnosis and ruling out certain hematologic disorders. While air‐drying is standard, some laboratories may use heat blocks to expedite drying. Excessive heat may induce morphologic artifacts, but there is a lack of systematic literature on this practice ...
Ryan C. Shean +4 more
wiley +1 more source
Ponatinib plus asciminib in myeloid blast-phase CML harboring a phased <i>BCR</i>::<i>ABL1</i> Y253H/T315I compound mutation: a case report. [PDF]
Front OncolHu Y, Ma H, He X.
europepmc +1 more source
ICSH Guidance on Bone Marrow Examination and Reporting
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber +6 more
wiley +1 more source
Reversal of protein chemical aging by enzymatic deglycation. [PDF]
Nat CommunTrabosh N +7 more
europepmc +1 more source