Data Mining for Identification of Targets and Repurposed Drugs to Eliminate Persistent Chronic Myeloid Leukaemia Stem Cells: Targeting RAS/RAF Signalling. [PDF]
Anggriawan IMB, Jørgensen HG.
europepmc +1 more source
Urologist and radiologist contributions to variation in prostate cancer detection at fusion biopsy
Objectives To quantify the relative contribution of radiologists and urologists to variability in clinically significant prostate cancer (CSPC) detection across multiparametric magnetic resonance imaging (mpMRI)‐guided prostate fusion biopsies and to determine whether this differed across Prostate Imaging‐Reporting And Data System (PI‐RADS) categories.
Daniel Triner +13 more
wiley +1 more source
Clinico-Metabolic Profiling Unraveled Key Metabolic Alterations Underlying the Pathophysiology of Chronic Myeloid Leukemia. [PDF]
Gupta S +5 more
europepmc +1 more source
Malignant craniopharyngiomas: Institutional experience and literature review
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen +10 more
wiley +1 more source
Evaluating large language models for pharmacotherapy simulations: a mixed-methods study. [PDF]
Farrag AN, El-Zeiny A, Ali AM.
europepmc +1 more source
ABSTRACT Aims In a phase 2 trial, the efficacy and safety of the highly selective aldosterone synthase inhibitor vicadrostat, alone or with empagliflozin, were investigated in people with chronic kidney disease (CKD) with or without type 2 diabetes (T2D). Materials and Methods Adults (n = 586) with CKD (estimated glomerular filtration rate [eGFR] 30 to
David Z. I. Cherney +14 more
wiley +1 more source
Site-specific evaluation of mutation-based mimics of histone glycation in the nucleosome. [PDF]
Dalilah Y, Simm A.
europepmc +1 more source
ABSTRACT Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) remains the only potentially curative therapy for many patients with high‐risk myeloid neoplasms, yet relapse and transplant‐related toxicity continue to limit durable benefit.
Mohammed Abdulgayoom +5 more
wiley +1 more source
Abnormal Eosinophils With Large, Distinctly Basophilic Granules (Harlequin Cells) on Peripheral Blood Smear: A Clue for Diagnosing Chronic Myeloid Leukemia. [PDF]
Cai J, Yue C, Tomassetti S.
europepmc +1 more source
ABSTRACT Aim To determine the effect of probiotic lozenges containing Lacticaseibacillus rhamnosus PB01, Latilactobacillus curvatus EB10 and xylitol after non‐surgical periodontal treatment (NSPT) on changes in microbial composition. The secondary aims were to assess the clinical and immunological impact of probiotic consumption.
Christine Marie Lundtorp‐Olsen +9 more
wiley +1 more source

