Results 141 to 150 of about 72,198 (215)

A PD1‐CD137L Fusion Protein More Potently Enhances Anti‐Tumour Immune Responses Than Targeting PD‐L1 and CD137 Separately

Immunology, EarlyView.
A PD1‐CD137L fusion protein converts the immunoinhibitory PD‐L1 to an immunostimulatory signal and is more effective than targeting PD‐L1 and CD137 separately. ABSTRACT Tumour immune evasion frequently involves PD‐L1‐mediated inhibition of T cell activity, limiting the efficacy of PD1/PD‐L1 blockade, particularly in PD‐L1‐low or immunologically ‘cold ...
Runze Xia, Emily Pauline Nickles, Yu Mei, Thamizhanban Manoharan, Yi Tian Png, Beijia Liu, Rui Sun, Kang Yi Lee, Gloryn Chia, Chwee Ming Lim, Herbert Schwarz   +10 more
wiley   +1 more source

A Case of Duffy-Null-Associated Neutropenia in a Patient With Chronic Myeloid Leukemia. [PDF]

Case Rep Hematol
Parekh A, Metzner-Sadurski J.
europepmc   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review. [PDF]

Med Oncol
Laurindo LO, Parente MLB, Sasahara GL, Goes JVC, Sampaio LR, Pinheiro YV, Pinheiro RF.   +6 more
europepmc   +1 more source

Histopathological and Molecular Data on Myxobolus spp. Infecting Bryconid Fish From the Brazilian Pantanal Wetland

Journal of Fish Diseases, EarlyView.
ABSTRACT Previous studies described Myxobolus umidus infecting the spleen of Brycon hilarii, whereas Myxobolus pantanalis and Myxobolus salminus infecting the gill filaments of Salminus brasiliensis. In this study, we provided supplementary morphological and molecular data on these three Myxobolus species and histopathological analyses of the tissues ...
Caroline Munhoz Meira, Milena Lucia Cornejo, Sarah Arana, Edson Aparecido Adriano, Antonio Augusto Mendes Maia   +4 more
wiley   +1 more source

Clonal and genomic determinants of e1a2 <i>BCR::ABL1</i> chronic myeloid leukemia: A Fi-LMC study. [PDF]

Hemasphere
Podvin B, Nibourel O, Hayette S, Coiteux V, Kim R, Rigolot L, Dulucq S, Boudry A, Pawlak G, Lambert WC, Flandrin-Gresta P, Sloma I, Roumier C, Balsat M, Loron S, Li C, Geffroy S, Cayuela JM, Huguet F, Mahon FX, Nicolini FE, Réa D, Preudhomme C, Duployez N, Roche-Lestienne C, Fi‐LMC group.   +25 more
europepmc   +1 more source

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

Journal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali, Jing Kang, Simon Haworth, Alessandro Polizzi, Gaetano Isola   +4 more
wiley   +1 more source

Distinguishing chronic myeloid leukemia in megakaryocytic blast crisis from <i>de novo</i> Ph+ acute megakaryoblastic leukemia: a case report and systematic review. [PDF]

Front Immunol
Liu Q, Yu P, Li X, Lan H, Liu Z.
europepmc   +1 more source

Duckweeds under salt stress: a meta‐analysis of growth inhibition in relation to morphological and physiological traits and a systematic review of molecular responses

New Phytologist, EarlyView.
Salinity reduces duckweed growth responses. Summary Salinity is one of the main environmental factors limiting the performance of duckweeds and despite growing ecological and biotechnological interest in these macrophytes, there is a lack of quantitative analyses of their responses to sodium chloride.
Saimon Branco Bueno, Alice Pita‐Barbosa, Ana Paula Roschildt, Daniel Burd Villanova, Janaina Cardozo de Mello, Alex Lindor, Tanise Luísa Sausen, Junior Borella   +7 more
wiley   +1 more source

Two novel e13a3 variants detected in CML patients and their DNA breakpoint analysis. [PDF]

Front Oncol
Liang D, Chang J, Xu Z, Ren F, Yang B, Chen X, Wang H.   +6 more
europepmc   +1 more source