Results 171 to 180 of about 70,006 (218)

Efficacy and Safety of Immune Checkpoint Inhibitors in the Treatment of Hematologic Malignancies: An Umbrella Review of Systematic Reviews and Meta‐Analyses

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background This umbrella review summarizes evidence from systematic reviews and meta‐analyses on the efficacy and safety of immune checkpoint inhibitors (ICIs) in hematologic malignancies. To our knowledge, this is the first umbrella review to comprehensively evaluate ICIs across multiple hematologic cancers.
Zhengyu Yu, Zhongwang Wang, Li Xie, Jing Xu, Lang Min, Lingfeng Li, Ting Niu   +6 more
wiley   +1 more source

A Current Overview of Quality-of-Life Research in Chronic Myeloid Leukemia (CML). [PDF]

Cancers (Basel)
Deneberg S.
europepmc   +1 more source

Stereoselective Production of Fluorohydrins Biocatalyzed by an Alcohol Dehydrogenase From Pichia glucozyma

ChemCatChem, Volume 18, Issue 11, 15 June 2026.
Ketoreductase from Pichia glucozyma (KRED1‐Pglu) has been successfully employed for the stereoselective bioreduction of α‐halogenated ketones using the purified protein, or alternatively a lyophilized whole cell preparation overexpressed in E. coli. Better chemoselectivities were found with pure biocatalyst, obtaining a series of chiral fluorohydrins ...
Marina García‐Ramos, Iván Lavandera, Francesco Molinari, Martina Letizia Contente, Vicente Gotor‐Fernández   +4 more
wiley   +1 more source

Case Report: Chronic myeloid leukemia in a 13-year-old-a rare pediatric case of extreme hyperleukocytosis in chronic phase. [PDF]

Front Med (Lausanne)
Asees M, Abdalhaq T, Amer J.
europepmc   +1 more source

Oral Lesions Developed in Post‐Hematopoietic Stem Cell Transplant Patients and the Role of Cryogun Cryotherapy

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objective To investigate the development of oral premalignant and malignant lesions as a major long‐term complication following hematopoietic stem cell transplantation. Methods This single‐center retrospective study identified 17 patients who developed 26 pathology‐confirmed oral premalignant and malignant lesions after hematopoietic stem cell
Pei Hsuan Lu, Kelly Yi Ping Liu, Samson P. Ng, Catherine F. Poh   +3 more
wiley   +1 more source

HTRS2025.P2.85 Sociodemographic disparities in thrombosis and bleeding rates in patients with myeloproliferative neoplasms: a real-world study from the Quebec MPN Research Group

Research and Practice in Thrombosis and Haemostasis
Sarah Côté-Denis, Lambert Busque, Sarah Côté-Denis, Michaël Harnois, Luigina Mollica, Harold Olney, Shireen Sirhan, Natasha Szuber   +7 more
doaj   +1 more source

Myeloproliferative neoplasms with concomitant chronic myeloid leukemia are associated with TKI resistance and poor outcomes. [PDF]

Leukemia
Gagnon LL, Duminuco A, Stagno F, Sobas M, Fominykh M, Virchis A, Nicolini FE, Hildt J, Bentley H, Godfrey AL, Shih LY, Chee A, Mead A, Lewandowski K, Sobieralski P, Hannah G, Reyal Y, Cummin T, Piszcz J, Yip K, Frewin R, Narayanan S, Rahman D, Ajayi A, Cervi P, Byrne J, Taylor T, Lebowa W, Pavlu J, Arami S, Ceesay M, Chraniuk D, Delage R, Condorelli A, Santana C, Radia DH, de Lavallade H, Milojkovic D, Harrison C, Harrington P.   +39 more
europepmc   +1 more source

Upcycling Agricultural By‐Products: RNA‐Seq‐Based Elucidation of Body Weight‐Independent Hepatoprotective Mechanisms of Cucumis melo var. makuwa Leaf Extract in Diet‐Induced Obese Mice

eFood, Volume 7, Issue 3, June 2026.
Upcycling agricultural by‐products into functional resources, this study demonstrates that Cucumis melo var. makuwa leaf (CML) extract exerts a marked weight‐independent improvement of hepatic steatosis. CML extract markedly alleviates lipid accumulation, oxidative stress, and inflammation in MASLD, highlighting its potent hepatoprotective and ...
Ji Young Hwang, Ji Yun Van, Hyeon Hak Jeong, Yerin Seong, Seokmin Lee, Jaeseong Seo, Bo‐Mi Ryu, Seungjun Lee, Suhyeon Baek, Sanggil Lee, Won‐Kyo Jung, Jae‐Il Kim, Bonggi Lee   +12 more
wiley   +1 more source

CIGB-258, a Potential Novel Approach to Treat Sepsis-like Hyperinflammation, Reduces Gastrointestinal Hemorrhage in Zebrafish Exposed to Carboxymethyllysine and Ethanol. [PDF]

Pharmaceuticals (Basel)
Cho KH, Lee Y, Lee SH, Bahuguna A, Domínguez-Horta MDC, Martínez-Donato G.   +5 more
europepmc   +1 more source

Bilateral ictal eye closure in focal epileptic seizures: SEEG retrospective observational assessment from a tertiary epilepsy center

Epileptic Disorders, Volume 28, Issue 3, Page 868-877, June 2026.
Abstract Ictal eye closure is commonly associated with functional seizures but may also occur in epileptic seizures. We retrospectively reviewed 113 consecutive stereo‐EEG (SEEG) recordings from adults with drug‐resistant focal epilepsy (2015–2024) to identify prolonged bilateral eye closure during seizures.
Paola Vassallo, Christina Pourlou, Joana F. A. Oliveira, Davide Giampiccolo, Charlotte McLaughlin, Emma Torzillo, Umair Javaid Chaudhary, John S. Duncan, Josemir W. Sander, Fahmida Chowdhury, Beate Diehl   +10 more
wiley   +1 more source