Results 71 to 80 of about 216,439 (378)

Temporal landmark validation in CML [PDF]

open access: yes2003 IEEE International Conference on Robotics and Automation (Cat. No.03CH37422), 2004
IEEE International Conference on Robotics and Automation (ICRA), 2003, Taipei (Taiwán)
Andrade-Cetto, Juan, Sanfeliu, Alberto
openaire   +3 more sources

An Introduction To The Web-Based Formalism [PDF]

open access: yes, 2016
This paper summarizes our rather lengthy paper, "Algebra of the Infrared: String Field Theoretic Structures in Massive ${\cal N}=(2,2)$ Field Theory In Two Dimensions," and is meant to be an informal, yet detailed, introduction and summary of that larger
Gaiotto, Davide   +2 more
core   +3 more sources

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

Phosphorylation-Dependent Differences in CXCR4-LASP1-AKT1 Interaction between Breast Cancer and Chronic Myeloid Leukemia

open access: yesCells, 2020
The serine/threonine protein kinase AKT1 is a downstream target of the chemokine receptor 4 (CXCR4), and both proteins play a central role in the modulation of diverse cellular processes, including proliferation and cell survival.
Elke Butt   +12 more
doaj   +1 more source

Treatment-free remission in CML: who, how, and why?

open access: yesHematology. American Society of Hematology. Education Program, 2017
Chronic myeloid leukemia (CML) is the best example of successful targeted therapy. Today, the overall survival of patients with CML treated by using tyrosine kinase inhibitors (TKIs) is very close to that of the healthy population.
F. Mahon
semanticscholar   +1 more source

Current treatment approaches in CML

open access: yesHemaSphere, 2019
Take home messages Five tyrosine kinase inhibitors are available, the treatment strategy is still challenging. Baseline risk, comorbidities, and patient and physician expectations play a pivotal role. Treatment-free remission is a new opportunity.
Castagnetti F.   +4 more
openaire   +5 more sources

Relation of common ABL kinase domain mutations with resistance to Tyrosine Kinase Inhibiters in patients with Chronic Myeloid Leukemia in Middle Euphrates of Iraq [PDF]

open access: yes, 2020
Background: Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease, associated with a reciprocal translocation between chromosomes 9 and chromosome 22, lead to the formation of the BCRABL fusion gene (Philadelphia chromosome).
Musawi, Mohammed Sadeq Mahdi Al-
core  

Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd   +8 more
wiley   +1 more source

Evaluating crop-specific responses to salinity and drought stress from remote sensing

open access: yesInternational Journal of Applied Earth Observations and Geoinformation, 2023
Food security is projected to be threatened by increasing co-occurring stresses (e.g., drought and salinity) under global climate change. To mitigate major impacts on food production, the tolerances and vulnerabilities of crops to these threats need to ...
Wen Wen   +3 more
doaj  

Cross-talk between Bcr-abl and the Thioredoxin System in Chronic Myeloid Leukaemia: Implications for CML Treatment

open access: yesAntioxidants, 2020
Chronic myeloid leukaemia (CML) is currently treated with inhibitors of the CML specific oncoprotein, bcr-abl. While this strategy is initially successful, drug resistance can become a problem.
Erin Clapper   +4 more
doaj   +1 more source

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