An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha +13 more
wiley +1 more source
A Review on Carbon‐Based and Metal‐Based Anode Materials of Microbial Fuel Cells
Reviews a wide range of anode materials used in microbial fuel cells (MFCs) and evaluates their performance and suitability for scalable energy recovery from wastewater. Defines the essential characteristics of an ideal anode, including high surface area, excellent electrical conductivity, strong biocompatibility, and cost‐effectiveness, while ...
Md. Hamidur Rahman +1 more
wiley +1 more source
Assessing the State of Comprehensive Medication Management in a Sample of Primary Care Clinics
Overview Comprehensive medication management (CMM) is an important tool to address medication-related morbidity and mortality and reduce health care costs.
Debbie Pestka +7 more
doaj +1 more source
Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Skin Type over Advancing Age of Males and Females: Evidence Estrogen and Androgenic Hair are Risk Factors [PDF]
We previously analyzed cutaneous malignant melanoma (CMM) incidences worldwide by sex, age, and Fitzpatrick skin type over time (1955-2007) and found only European-ancestry populations have exponential increasing incidences and about a 2-log increase in ...
Godar, Dianne E. +2 more
core +1 more source
Uji Inokulasi dan Respon Ketahanan 38 Genotipe To Mat terhadap Clavibacter Michiganensis Subsp. Michiganensis [PDF]
Identifi kasi ketahanan genotipe adalah langkah awal dalam pengembangan kultivar tahan terhadap serangan patogen. Tujuan penelitian ini adalah (i) mendapatkan cara inokulasi dengan jumlah dan konsentrasi inokulum Cmm yang efektif untuk mengevaluasi ...
Anwar, A. (Aswaldi) +4 more
core
ABSTRACT Background The teaching of occlusal splint therapy in dental education is evolving with the integration of digital workflows. Although digital tools offer operational advantages, conventional methods remain pedagogically relevant. Understanding students’ perceptions of both approaches is essential for guiding curriculum innovation.
Marcelo José Palma‐Fernandes +6 more
wiley +1 more source
Penelitian ini bertujuan mengevaluasi keragaman karakter morfologi dan agronomi 13 populasi F 1 half-sibubi kayu di Bandar Lampung. Evaluasi dilaksanakan pada bulan Maret 2016 – Februari 2017. Populasihalf-sib merupakan keturunan tetua betina Adira, CMM,
Kronika J A Silalahi +3 more
doaj +1 more source
90 degree polarization rotator using a bilayered chiral metamaterial with giant optical activity
A bilayered chiral metamaterial (CMM) is proposed to realize a 90 degree polarization rotator, whose giant optical activity is due to the transverse magnetic dipole coupling among the metallic wire pairs of enantiomeric patterns.
Jackson J. D. +3 more
core +1 more source
ABSTRACT Background Routine collection of patient perspectives about psoriasis and its treatment through patient reported outcome measurements (PROMs), alongside clinician reported outcome measurements (CROMs), may improve clinical outcomes and facilitate shared decision making.
Jaime Notario +7 more
wiley +1 more source
Association Research between Relative Fat Mass and the Incidence Risk of Cardiometabolic Multimorbidity [PDF]
Background Cardiometabolic multimorbidity (CMM) represents one of the most prevalent and stable multimorbidity patterns. Relative fat mass (RFM), as a novel anthropometric indicator for assessing adiposity, has shown promise as a predictor of individual ...
GU Handong, LU Hongrun, GU Keyi, HAN Zheng, YANG Fei, FU Xiaoya, WANG Weiqiang
doaj +1 more source

