Results 101 to 110 of about 17,015 (238)

CMM 2019, Coimbra [PDF]

open access: yesSteel Construction, 2020
Luís Simões da Silva, Paulo Vila Real
openaire   +1 more source

Phenotypes and clinical outcomes in children with moderate‐to‐severe atopic dermatitis across diverse ancestries: a Spanish multicenter observational study and cluster analysis (AD‐SKINS Project)

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Atopic dermatitis (AD) has a highly variable clinical phenotype and ancestry can contribute to this heterogeneity. This study aims to identify clinical phenotypes of AD in children from diverse ancestry groups, evaluate clinical outcomes and response to treatment, and define phenotypic clusters with potential relevance.
Eugeni Prat‐Colilles   +21 more
wiley   +1 more source

Intervention outcomes of children with non‐degenerative dystonia and associated hyperkinetic movement disorders: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify the outcomes reported in published studies of intervention approaches used with non‐degenerative childhood hyperkinetic movement disorders, including dystonia, dyskinesia, hypertonia, athetosis, chorea, cerebral palsy, involuntary movement, and kernicterus, and map them to the International Classification of Functioning ...
Hortensia Gimeno   +10 more
wiley   +1 more source

Genetic testing in paediatric neurological disorders

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
In this study 390 paediatric patients with neurological disorders underwent genetic testing via exome sequencing, commercial panel, in‐house epilepsy, and movement disorder gene panels. Exome sequencing provides the highest diagnostic yield, and severe developmental delay and hypotonia predicted pathogenic variants in the exome sequencing cohort ...
Wafa Bani Uraba   +15 more
wiley   +1 more source

Obesity and the Development of Cardiometabolic Multimorbidity: A Cross‐Lagged Panel Network Analysis of Three National Chinese Cohorts

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To explore longitudinal and bidirectional associations between obesity and cardiometabolic diseases (CMDs) using a cross‐lagged panel network (CLPN) framework in three nationally representative Chinese cohorts. Materials and Methods We analysed participants aged 45 years and older from CHARLS (2011–2015; n = 12 491), CHNS (2004–2015; n ...
Zeping Fang, Jinli Liu, Lei Zhang
wiley   +1 more source

Forest edges buffer effects of agricultural management on bee–plant interaction networks

open access: yesEcological Entomology, EarlyView.
Agricultural management effects: Organic and conventional crop margins host similar bee and plant species, but network structure differs: organic farms exhibit higher interaction diversity, conventional farms higher connectance. Role of forest edges: Native forest edges stabilize bee–plant networks by providing continuous floral resources and suitable ...
Samantha Marx de Castro   +6 more
wiley   +1 more source

Impact of an Educational Intervention on Dental Students' Practical Motivation in Early Oral Cancer Detection: Assessment With the “Perceived Locus of Causality–University Version” Questionnaire

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction Early detection of oral cancer significantly improves prognosis, but diagnostic delays persist due to professional and educational factors. This study aimed to evaluate the impact of an educational intervention on dental students' motivation toward oral cancer detection, using the Perceived Locus of Causality–University Version ...
Esther Delgado‐Somolinos   +7 more
wiley   +1 more source

Newly identified human aminoacyl‐tRNA synthetase complex interacting multifunctional protein 2 (AIMP2) loss‐of‐function mutations cause neurodevelopmental defects linked to cell death in a zebrafish model

open access: yesThe FEBS Journal, EarlyView.
Human AIMP2 mutations lead to severe neurodevelopmental defects and brain atrophy. Using patient‐derived fibroblasts from two individuals, we show decreased AIMP2 protein levels and overall protein synthesis. In a zebrafish loss‐of‐function model, the lack of AIMP2 leads to an increase in cell death and results in smaller brains.
Patrick Mullen   +10 more
wiley   +1 more source

Use of an Oral Health‐Related Quality of Life Instrument to Measure Unmet Dental Care Needs in Adults With Inherited Bleeding Disorders

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Preventive dental care is vital for individuals with bleeding disorders to reduce the need for potentially invasive procedures. Although dental care is a mandated function of U.S. federally supported hemophilia treatment centers (HTCs), access to dental care is widely variable.
Miguel A. Escobar   +4 more
wiley   +1 more source

Association of Interleukin‐17F Polymorphisms (rs763780, rs9382084, rs2397084, and rs12203582) With Gastric Cancer Susceptibility According to Helicobacter pylori Infection Status

open access: yesInternational Journal of Immunogenetics, EarlyView.
ABSTRACT Single nucleotide polymorphisms (SNPs) in the interleukin‐17F (IL‐17F) gene may modulate inflammatory responses, with distinct effects on inflammation and tumour progression. Helicobacter pylori infection, a Group 1 carcinogen, is strongly associated with gastric cancer (GC) development.
Mikaela Nagahara   +9 more
wiley   +1 more source

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