Results 141 to 150 of about 88,126 (251)

Five‐Minute Apgar Scores and Its Prognostic Value for Mortality and Severe Morbidity in Very Preterm Infants: A Multinational Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 649-659, March 2026.
ABSTRACT Objective To examine associations between a 5‐min Apgar score < 7 and severe neonatal outcomes in very preterm (VPT) infants and how results are impacted by variations in assigning Apgar scores within an international context. Design Prospective observational population‐based cohort study.
Harald Ehrhardt   +79 more
wiley   +1 more source

Steering Digital Transformation: An Iterative Landscape Approach

open access: yesInformation Systems Journal, Volume 36, Issue 2, Page 299-312, March 2026.
ABSTRACT Digital transformation (DT) is in the limelight of organisations and society. However, it is challenging to steer a DT endeavour, which is also difficult to assess because of its complex nature. Instead of focusing solely on the typical end result of DT, we propose using a DT landscape approach.
Léon‐Paul de Rouw   +3 more
wiley   +1 more source

Evaluating VEGFR2 as a Target for Anti‐Tumour Therapy in Canine Melanoma

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 1, Page 95-104, March 2026.
ABSTRACT Vascular endothelial growth factor receptor 2 (VEGFR2) is a key target for anti‐angiogenic oncotherapy, as inhibiting this receptor on tumour vasculature slows tumour development and enhances drug‐ and immune infiltration, improving therapy outcome.
Esther Hindriks   +5 more
wiley   +1 more source

Toward Producing Supertough PET: Synergistic Action of Bio‐LDPE and LDPE‐g‐MA in Reactive Processing

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 5, February 5, 2026.
Reactive processing and the appropriate concentration of Bio‐LDPE and LDPE‐g‐MA have the potential to supertough PET at room temperature, contributing to the expansion of its application range. ABSTRACT New blends of poly(ethylene terephthalate) (PET) and bio‐based low‐density polyethylene (Bio‐LDPE) were developed and compatibilized with low‐density ...
Clara Maria Marinho Serafim   +5 more
wiley   +1 more source

Clinical Correlates of Anxiety and Depression After Diagnosis of a Pediatric Brain Tumor

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background The prevalence and clinical correlates of symptoms of anxiety and depression in pediatric patients with brain tumors are not well described. We aimed to identify clinical characteristics that are correlated with elevated symptoms of anxiety and depression following initial diagnosis.
Bryony J. Lucas   +16 more
wiley   +1 more source

Thermal Phase‐Modulation of Thickness‐Dependent CVD‐Grown 2D In2Se3

open access: yesAdvanced Functional Materials, Volume 36, Issue 12, 9 February 2026.
A comprehensive study of CVD‐grown 2D In2Se3 reveals a distinct thickness‐dependent phase landscape and a reversible, thermally driven transformation between β″ and β* variants. In situ TEM electron diffraction and Raman spectroscopy reveal structural dynamics, while the structural invariance of the α‐phase in ultrathin regimes highlights its stability—
Dasun P. W. Guruge   +6 more
wiley   +1 more source

An experimental medicine protocol for exploring the haemodynamic effects of dual agonism at the glucagon‐like peptide‐1 and glucagon receptor in healthy subjects

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 579-588, February 2026.
Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman   +13 more
wiley   +1 more source

Characterization of a deformable beating cardiac phantom with real‐time dosimetric capabilities for validation of MRI‐guided heart radiotherapy

open access: yesMedical Physics, Volume 53, Issue 2, February 2026.
Abstract Background Stereotactic arrhythmia radioablation (STAR) has emerged as a salvage treatment for patients with ventricular tachycardia, and the MR‐linacs offer MRI‐guidance during such treatment. However, available workflows on MR‐linacs are not yet optimized and characterized dedicatedly to perform heart radiotherapy due to a lack of realistic ...
Manon M. N. Aubert   +10 more
wiley   +1 more source

Cognitive Profiles in Adolescents and Young Adults With Co‐Occurring Autism and First‐Episode Psychosis: A Preliminary Neuropsychological Investigation

open access: yesPsyCh Journal, Volume 15, Issue 1, February 2026.
ABSTRACT Autism spectrum disorder (ASD) and psychosis are traditionally considered distinct psychiatric conditions with divergent developmental trajectories, yet emerging evidence suggests they may share overlapping neurodevelopmental characteristics.
Domily T. Y. Lau   +6 more
wiley   +1 more source

Development of a Pregnancy‐Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders. Despite aspirin's widespread use in pregnancy for preeclampsia prevention, its pharmacokinetics (PK) across all trimesters remain poorly characterized, complicating optimal dosing recommendations. To develop a pregnancy‐
Ana Collins‐Smith   +5 more
wiley   +1 more source

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