Results 141 to 150 of about 88,126 (251)
ABSTRACT Objective To examine associations between a 5‐min Apgar score < 7 and severe neonatal outcomes in very preterm (VPT) infants and how results are impacted by variations in assigning Apgar scores within an international context. Design Prospective observational population‐based cohort study.
Harald Ehrhardt +79 more
wiley +1 more source
Steering Digital Transformation: An Iterative Landscape Approach
ABSTRACT Digital transformation (DT) is in the limelight of organisations and society. However, it is challenging to steer a DT endeavour, which is also difficult to assess because of its complex nature. Instead of focusing solely on the typical end result of DT, we propose using a DT landscape approach.
Léon‐Paul de Rouw +3 more
wiley +1 more source
Evaluating VEGFR2 as a Target for Anti‐Tumour Therapy in Canine Melanoma
ABSTRACT Vascular endothelial growth factor receptor 2 (VEGFR2) is a key target for anti‐angiogenic oncotherapy, as inhibiting this receptor on tumour vasculature slows tumour development and enhances drug‐ and immune infiltration, improving therapy outcome.
Esther Hindriks +5 more
wiley +1 more source
Toward Producing Supertough PET: Synergistic Action of Bio‐LDPE and LDPE‐g‐MA in Reactive Processing
Reactive processing and the appropriate concentration of Bio‐LDPE and LDPE‐g‐MA have the potential to supertough PET at room temperature, contributing to the expansion of its application range. ABSTRACT New blends of poly(ethylene terephthalate) (PET) and bio‐based low‐density polyethylene (Bio‐LDPE) were developed and compatibilized with low‐density ...
Clara Maria Marinho Serafim +5 more
wiley +1 more source
Clinical Correlates of Anxiety and Depression After Diagnosis of a Pediatric Brain Tumor
ABSTRACT Background The prevalence and clinical correlates of symptoms of anxiety and depression in pediatric patients with brain tumors are not well described. We aimed to identify clinical characteristics that are correlated with elevated symptoms of anxiety and depression following initial diagnosis.
Bryony J. Lucas +16 more
wiley +1 more source
Thermal Phase‐Modulation of Thickness‐Dependent CVD‐Grown 2D In2Se3
A comprehensive study of CVD‐grown 2D In2Se3 reveals a distinct thickness‐dependent phase landscape and a reversible, thermally driven transformation between β″ and β* variants. In situ TEM electron diffraction and Raman spectroscopy reveal structural dynamics, while the structural invariance of the α‐phase in ultrathin regimes highlights its stability—
Dasun P. W. Guruge +6 more
wiley +1 more source
Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman +13 more
wiley +1 more source
Abstract Background Stereotactic arrhythmia radioablation (STAR) has emerged as a salvage treatment for patients with ventricular tachycardia, and the MR‐linacs offer MRI‐guidance during such treatment. However, available workflows on MR‐linacs are not yet optimized and characterized dedicatedly to perform heart radiotherapy due to a lack of realistic ...
Manon M. N. Aubert +10 more
wiley +1 more source
ABSTRACT Autism spectrum disorder (ASD) and psychosis are traditionally considered distinct psychiatric conditions with divergent developmental trajectories, yet emerging evidence suggests they may share overlapping neurodevelopmental characteristics.
Domily T. Y. Lau +6 more
wiley +1 more source
Development of a Pregnancy‐Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin
ABSTRACT Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders. Despite aspirin's widespread use in pregnancy for preeclampsia prevention, its pharmacokinetics (PK) across all trimesters remain poorly characterized, complicating optimal dosing recommendations. To develop a pregnancy‐
Ana Collins‐Smith +5 more
wiley +1 more source

