Results 11 to 20 of about 63,222 (303)
Ribonucleotides Amplify Mitochondrial DNA-Driven cGAS-STING Activation via FdUMP-ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy. [PDF]
Adv Sci (Weinh)This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Wang C +10 more
europepmc +2 more sources
CMP-sialic acid transporter trafficking, Golgi localization, and functional organization.
, 2009 CMP-sialic acid transporter trafficking, Golgi localization, and functional ...
Weihan. Zhao (7980293)
core +6 more sources
Two New Matrix Classes Related to the CMP Inverse: CMP and Co-CMP Matrices
Mathematics, 2023 This paper focuses on two new matrix classes related to the CMP inverse of a square matrix, called the CMP and co-CMP matrices. Some of their characterizations are identified based on the core-EP decomposition and subspace operations. And, we show an equivalence relationship between the co-CMP matrix set and the intersection of the core matrix set and ...
Yinlan Chen, Jiale Gao, Kezheng Zuo
openaire +2 more sources
Filtering directory lookups in CMPs [PDF]
Microprocessors and Microsystems, 2010 Coherence protocols consume an important fraction of power to determine which coherence action should take place. In this paper we focus on CMPs with a shared cache and a directory-based coherence protocol implemented as a duplicate of local caches tags. We observe that a big fraction of directory lookups produce a miss since the block looked up is not
Ana Bosque +3 more
openaire +5 more sources
Adaptive and Speculative Slack Simulations of CMPs on CMPs
2010 43rd Annual IEEE/ACM International Symposium on Microarchitecture, 2010 Current trends signal an imminent crisis in the simulation of future CMPs (Chip Multiprocessors). Future micro-architectures will offer more and more thread contexts to execute parallel programs, but the execution speed of each thread will not improve at the same pace. CMPs with 10’s or even100’s of cores are envisioned.
Jianwei Chen +4 more
openaire +3 more sources
CPU Accounting in CMP Processors [PDF]
IEEE Computer Architecture Letters, 2009 Chip-MultiProcessors (CMP) introduce complexities when accounting CPU utilization to processes because the progress done by a process during an interval of time highly depends on the activity of the other processes it is co-scheduled with. We propose a new hardware accounting mechanism to improve the accuracy when measuring the CPU utilization in CMPs ...
Carlos Luque +5 more
openaire +2 more sources
Applications of chemical mechanical planarization (CMP) to More than Moore devices
, 2022 S.463-485In addition to the ongoing increase in memory capacity and microprocessor performance of devices ("More Moore"), other functionalities like analogue/RF devices, passive components, high voltage and power transistors, sensors and actuators (MEMS,
Zwicker, G.
core +1 more source
CMP process development for Cobalt liner integration at the 28-nm-node
, 2022 S.62Advanced liner materials are crucial for optimizing and further shrinking of integrated circuits' interconnects. For next generation devices there is a focus on Cobalt (Co) and Ruthenium (Ru) [1]. Besides the challenges to deposit such materials, new
Wislicenus, M. +8 more
core +1 more source
ICPT 2012, International Conference on Planarization/CMP Technology. Proceedings
, 2022 As the result of increased co-operation between local CMP users groups in Europe, Japan, Korea, Taiwan, and the United States of America, the International Conference on Planarization/CMP Technology ICPT has been established as the most respected annual ...
core +1 more source
Inhibition of CMP-sialic acid transport by endogenous 5-methyl CMP [PDF]
PLOS ONE, 2020 Abstract Nucleotide-sugar transporters (NSTs) transport nucleotide-sugar conjugates into the Golgi lumen where they are then used in the synthesis of glycans. We previously reported crystal structures of a mammalian NST, the CMP-sialic acid transporter (CST) (Ahuja and Whorton 2019).
Shivani Ahuja +3 more
openaire +4 more sources