Distinct Urea Cycle Dysfunction Profiles Differentiate Acute Metabolic Decompensation in TMEM70 and MT-ATP6-Related Mitochondrial ATP Synthase Defects. [PDF]
J Inherit Metab DisSiri B +8 more
europepmc +1 more source
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 9, Page 1234-1247, November 2026.In this nationwide ENEIDA registry study, anti‐TNF therapy after prior exposure to a different biologic mechanism of action showed reduced treatment durability in inflammatory bowel disease, with a particularly marked impact in ulcerative colitis, where short‐ and long‐term clinical effectiveness was also lower. ABSTRACT Background The expanding use of
Carmen Yagüe Caballero +85 more
wiley +1 more source
Inhibition of LIMK by Cofilin-1 peptidomimetics enhances actin depolymerization and reduces metastasis of non-small cell lung cancer. [PDF]
OncogenesisLin MY, Leu JD, Wu CY, Chen LC, Lee YJ.
europepmc +1 more source
Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta
Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng +7 more
wiley +1 more source
A novel immersion chemical mechanical polishing device and tailored slurry for processing heavy duty gas turbine compressor blades. [PDF]
Sci RepLi Q +8 more
europepmc +1 more source
The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review
The FASEB Journal, Volume 40, Issue 20, 31 October 2026.Proposed mechanisms by which cannabidiol (CBD) promotes cutaneous wound healing. CBD modulates inflammatory and oxidative pathways, enhances fibroblast migration and proliferation, stimulates collagen deposition and extracellular matrix remodeling, and promotes angiogenesis, collectively contributing to improved tissue repair. ABSTRACT Cutaneous wounds
João Henrique Ferreira França +7 more
wiley +1 more source
Pediatric heart failure: A focus on low-income countries. [PDF]
World J Clin PediatrAli SK.
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, Volume 600, Issue 19, Page 2947-2960, October 2026.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Converting focused ultrasound-based boiling histotripsy into a systemic cancer vaccine using antigen-capturing microparticles. [PDF]
TheranosticsSingh A +6 more
europepmc +1 more source
Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions
Annals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2134-2137, October 2026.ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos +5 more
wiley +1 more source