Results 61 to 70 of about 204,897 (299)

Dynamic finite-strain modelling of the human left ventricle in health and disease using an immersed boundary-finite element method [PDF]

, 2014
Detailed models of the biomechanics of the heart are important both for developing improved interventions for patients with heart disease and also for patient risk stratification and treatment planning.
Berry, Colin, Carrick, David, Gao, Hao, Griffith, Boyce E., Luo, Xiaoyu   +4 more
core   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Sergentomyia (Neophlebotomus) chattiensis n. sp.: morphological and molecular description of a new sand fly species from Himachal Pradesh, India

Frontiers in Insect Science
IntroductionHimachal Pradesh, an ecologically diverse state in northern India, has recently emerged as a focus of atypical cutaneous leishmaniasis. As part of a molecular xenomonitoring, systematic entomological surveillance of sand flies resulted in the
Harish Kumar Shah, P. A. Fathima, Manju Rahi, Prasanta Saini   +3 more
doaj   +1 more source

Synoptic Conditions Generating Important Snowfalls and Their Relation with Avalanches in 2015-2016 Winter. [PDF]

Aerul şi Apa: Componente ale Mediului, 2017
The paper presents and analyzes variations in weather conditions, meteorological and nivological (snow related) parameters that favored avalanches triggering in Bucegi and Făgăraş Mountains during 2015-2016 winter, an area monitored by the program for ...
C. GRECU, A. PAŞOL, Narcisa MILIAN, U. RECKERTH   +3 more
doaj   +1 more source

Perception of neighborhood crime and drugs Increases cardiometabolic risk in Chilean adolescents [PDF]

, 2014
PURPOSE: Studies report an association between neighborhood risk and both obesity and cardiometabolic risk factors (CMR) among adolescents. Here we describe the effect of perceived neighborhood risk on adiposity and CMR among Chilean adolescents ...
Blanco, Estela, Burrows, Raquel, Delva, Jorge, Gahagan, Sheila, Lozoff, Betsy, Martinez, Suzanna M., Reyes, Marcela   +6 more
core   +2 more sources

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Spin-lattice coupling effects in the Holstein double-exchange model

, 2004
Based on the Holstein double-exchange model and a highly efficient single cluster Monte Carlo approach we study the interplay of double-exchange and polaron effects in doped colossal magneto-resistance (CMR) manganites.
Alexander Weiße, Alonso, Dieter Ihle, Fehske, Holger Fehske, Ihle, Janke, Millis, Motome, Motome, Silver, Weiße, Weiße, Wolff   +13 more
core   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

The REFLO-STEMI (REperfusion Facilitated by LOcal adjunctive therapy in ST-Elevation Myocardial Infarction) trial: a randomised controlled trial comparing intracoronary administration of adenosine or sodium nitroprusside with control for attenuation of microvascular obstruction during primary percutaneous coronary intervention

Efficacy and Mechanism Evaluation, 2016
Background: Microvascular obstruction (MVO) predicts short- and longer-term outcomes following primary percutaneous coronary intervention (PPCI) treatment of ST-elevation myocardial infarction (STEMI).
Sheraz A Nazir, Jamal N Khan, Islam Z Mahmoud, John P Greenwood, Daniel J Blackman, Vijay Kunadian, Martin Been, Keith R Abrams, Robert Wilcox, AA Jennifer Adgey, Gerry P McCann, Anthony H Gershlick   +11 more
doaj   +1 more source

Sustainable Productivity Growth in Agriculture: The Role of Shifts in R&D Investments and Technology

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT The objective of the paper is to evaluate the long‐term prospects of sustainable productivity growth linked to plausible assumptions on public agricultural R&D investments as the key productivity driver. Second, it investigates the role of changing R&D focus from yield maximization to input saving technologies (fertilizers and pesticides). The
Zuzana Smeets Křístková, Michiel van Dijk, Robert M'Barek, Hans van Meijl, Tomas Ratinger   +4 more
wiley   +1 more source