Results 11 to 20 of about 2,156 (154)

Metabolomic Signatures and Machine Learning Models for Distinguishing Alzheimer's Disease and Dementia with Lewy Bodies [PDF]

Alzheimers Dement
Abstract Background Alzheimer's Disease (AD) and Dementia with Lewy Bodies (DLB) are difficult to distinguish clinically due to overlapping symptoms, resulting in delayed or incorrect diagnoses. This study uses metabolomic profiles from serum samples and machine learning models to identify key biomarkers that distinguish these conditions.
Mukesha D, Sarter M, Dubray M, Durand F, KUL S, Pham‐Van L, BOUTILLIER S, Sacco G, FIRAT H.   +8 more
europepmc   +4 more sources

Advancing whole-brain BOLD functional MRI in humans at 10.5 T with motion-robust 3D echo-planar imaging, parallel transmission, and high-density radiofrequency receive coils. [PDF]

Magn Reson Med
Abstract Purpose To demonstrate the feasibility and performance of whole‐brain blood oxygen level–dependent functional MRI (fMRI) in humans at 10.5 T by combining motion‐robust three‐dimensional gradient‐echo echo‐planar imaging, parallel transmission, and high‐density radiofrequency (RF) receive coils.
Qu S, Liu J, van Gelderen P, de Zwart JA, Duyn JH, Waks M, Lagore R, Bratch A, Grant A, Auerbach E, Delabarre L, Sadeghi-Tarakameh A, Eryaman Y, Adriany G, Ugurbil K, Wu X.   +15 more
europepmc   +2 more sources

A CMRR enhancement circuit by employing auxiliary buffer of capacitively coupled instrumentation amplifier for neural signal recording

Electronics Letters, 2021
Here, a common‐mode rejection ratio (CMRR) enhancement circuit is proposed by employing an auxiliary buffer (AB) to the pseudo resistors of the capacitively coupled instrumentation amplifier (CCIA).
Longbin Zhu, Zhijun Zhou, Chiyuan Zhang, Qiao Meng, Zhi‐gong Wang   +4 more
doaj   +1 more source

Brain fMRI during orientation selective epidural spinal cord stimulation

Scientific Reports, 2021
Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury.
Antonietta Canna, Lauri J. Lehto, Lin Wu, Sheng Sang, Hanne Laakso, Jun Ma, Pavel Filip, Yuan Zhang, Olli Gröhn, Fabrizio Esposito, Clark C. Chen, Igor Lavrov, Shalom Michaeli, Silvia Mangia   +13 more
doaj   +1 more source

Cortical layer-specific differences in stimulus selectivity revealed with high-field fMRI and single-vessel resolution optical imaging of the primary visual cortex

NeuroImage, 2022
The mammalian neocortex exhibits a stereotypical laminar organization, with feedforward inputs arriving primarily into layer 4, local computations shaping response selectivity in layers 2/3, and outputs to other brain areas emanating via layers 2/3, 5 ...
Shinho Cho, Arani Roy, Chao J. Liu, Djaudat Idiyatullin, Wei Zhu, Yi Zhang, Xiao-Hong Zhu, Phillip O'Herron, Austin Leikvoll, Wei Chen, Prakash Kara, Kâmil Uğurbil   +11 more
doaj   +1 more source

Building resilience for successful aging : developing resources and protective factors to overcome life's challenges with confidence [PDF]

Alzheimers Dement
Abstract Background Resilience, a key factor in successful aging, defined as the ability to adapt positively to adversity. Research shows that resilience protects against cognitive decline and is associated with better cognitive functioning, greater autonomy, improved quality of life, and enhanced psychological well‐being. As a key factor in aging well,
Ferrandez y Montesinos M, Filleau C, Manera V, Corveleyn X.   +3 more
europepmc   +2 more sources

Study of blood biomarkers detected in NULISA to stratify the prospective multicenter ALZAN cohort of memory clinic patients according to ATN status, presence of synucleinopathy and diagnosis [PDF]

Alzheimers Dement
Abstract Background The objective of this study in the multicenter prospective ALZAN cohort is to assess the performance of blood biomarkers for detecting biological processes based on the ATN classification and synuclein seed amplification assay (SAA), as well as for diagnosing Alzheimer's disease (AD) and related dementias, including frontotemporal ...
Lehmann S, Delaby C, Pradeilles N, Assou S, Hirtz C, Busto G, Dupuy B, Duchiron M, Morchikh M, Barnier‐Figue G, Perrein F, Gabelle A, Turpinat C, Jurici S, Bennys K.   +14 more
europepmc   +2 more sources

The PREVCOG study: longitudinal and multimodal biomarker analyses for secondary prevention of Alzheimer's disease and cognitive decline in French memory clinics [PDF]

Alzheimers Dement
Abstract Background While research on Alzheimer's disease has recently made significant progress with the approval of two disease‐modifying treatments and the development of blood‐based biomarkers predicted to revolutionize AD diagnosis, questions remain—particularly regarding the value of amyloidopathy in predicting cognitive decline on its own.
Busto G, Turpinat C, Navucet S, Bars E, Dauvilliers Y, Delrieu J, Perrein F, Jurici S, Claeysen S, Gabelle A, Lehmann S, Bennys K.   +11 more
europepmc   +2 more sources

10.5 T In Vivo Head Imaging With Universal RF Shimming. [PDF]

Magn Reson Med
ABSTRACT Purpose Brain MR imaging at 10.5 T ultra‐high field offers significant improvements in signal‐to‐noise ratio (SNR), but faces challenges with B1+ inhomogeneity. Parallel‐transmission (pTx) can be used to achieve a more uniform RF field distribution, but necessitates the use of B1+ calibration in the region of interest.
Park YW, Schmidt S, Bogner W, Metzger GJ, Marjańska M.   +4 more
europepmc   +2 more sources

Investigation of factors influencing roof stability at a Western U.S. longwall coal mine

International Journal of Mining Science and Technology, 2019
The coal mine roof rating (CMRR) was developed to bridge the gap between geological variation in underground coal mines and engineering design. The CMRR accounts for the compressive strength of the immediate roof, the shear strength and intensity of any ...
Meriel Young, Gabriel Walton, Elizabeth Holley   +2 more
doaj   +1 more source