Results 71 to 80 of about 16,762 (235)

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Experimental Investigation of Performance and Emissions of a Stratified Charge CNG Direct Injection Engine with Turbocharger

open access: yesMATEC Web of Conferences, 2017
This paper presents the results from 1.6 litre, 4 cylinders stratified charge compressed natural gas (CNG) direct injection engine with boosting device. A turbocharger with compressor trim of 40 was used to increase engine output.
Amiruddin Hilmi   +4 more
doaj   +1 more source

Dual IRE1 targets: Determinants of the cell fate?

open access: yesThe FEBS Journal, EarlyView.
IRE1 is an ER stress sensor that restores protein homeostasis through two signaling activities: XBP1s, which upregulates its target gene expression or RIDD which downregulates its target transcripts. We recently identified Dual IRE1 Targets (DIT) which are modulated by both XBP1s and RIDD activities.
Eva Billat   +3 more
wiley   +1 more source

Existência da “Serra do Mar” no Rio Grande do Sul

open access: yesBoletim Geográfico do Rio Grande do Sul, 2014
Responde a um pedido de informação sobre ser errada qualquer referência à “Serra do Mar” no Rio Grande do Sul. Destina-se aos professores do Magistério Estadual.
Maria Luiza Lessa de Curtis
doaj  

CP32, a novel anti‐oomycete cyclic peptide, interferes with cell‐wall deposition in Phytophthora infestans

open access: yesJournal of Integrative Plant Biology, EarlyView.
The small cyclic peptide CP32 effectively inhibits Phytophthora infestans, the causal agent of potato and tomato late blight. Combined biochemical and phenotypic analyses demonstrate that CP32 disrupts cell wall biosynthesis, a key process in pathogen infection, resulting in a marked reduction of disease symptoms in plants.
Demetrio Marcianò   +23 more
wiley   +1 more source

Excursão à região colonial antiga do Rio Grande do Sul

open access: yesBoletim Geográfico do Rio Grande do Sul, 2014
Versa sobre o reconhecimento geográfico advindo das observações feitas em campo e sobre a descrição da paisagem em diferentes áreas do estado.
Orlando Valverde
doaj  

Más allá de las palabras. Encontrando centros de gravedad narrativa en animales no lingüísticos

open access: yesIdeas y Valores
Dennett’s theory of the self as a center of narrative gravity (CNG) highlights human exceptionalism amid a philosophy emphasizing evolutionary continuity.
Amber Ross
doaj   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

PERHITUNGAN HARGA POKOK PRODUK COMPRESSED NATURAL GAS DARI LANDFILL GAS SEBAGAI ENERGI ALTERNATIF PADA TPST BANTAR GEBANG, BEKASI

open access: yesJ@ti Undip: Jurnal Teknik Industri, 2013
Pergeseran konsumsi bahan bakar minyak ke bahan bakar berbasis gas, sebagai alternatif energi untuk sektor transportasi di Indonesia diperlukan. Salah satu renewable energy yang saat ini populer adalah biogas.
Srilarakasuri P Ardiagarini   +2 more
doaj   +1 more source

Electrified Carbon‐Neutral Methanol Production Pathways: A Multiscale Techno‐Economic‐Environmental Assessment Based on the UK Energy System

open access: yesAdvanced Chemical Engineering, Volume 1, Issue 2, December 2026.
A two‐scale framework bridges process‐level physics and system‐level decision‐making for electrified green methanol production. Replacing computationally demanding reactor simulations with an interpretable symbolic‐regression surrogate enables rapid techno‐economic and life‐cycle assessment. The framework reveals how process performance propagates into
Yuanjing Zhao   +5 more
wiley   +1 more source

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