Electrophysiological evaluation of the effect of peptide toxins on voltage-gated ion channels: a scoping review on theoretical and methodological aspects with focus on the Central and South American experience [PDF]
The effect of peptide toxins on voltage-gated ion channels can be reliably assessed using electrophysiological assays, such as the patch-clamp technique.
Jessica Rojas-Palomino+5 more
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Venom system variation and the division of labor in the colonial hydrozoan Hydractinia symbiolongicarpus. [PDF]
Cnidarians (jellyfish, hydroids, sea anemones, and corals) possess a unique method for venom production, maintenance, and deployment through a decentralized system composed of different types of venom-filled stinging structures called nematocysts.
Klompen AML, Sanders SM, Cartwright P.
europepmc +3 more sources
Localization of Multiple Jellyfish Toxins Shows Specificity for Functionally Distinct Polyps and Nematocyst Types in a Colonial Hydrozoan. [PDF]
Hydractinia symbiolongicarpus is a colonial hydrozoan that displays a division of labor through morphologically distinct and functionally specialized polyp types.
Klompen AML, Travert MK, Cartwright P.
europepmc +3 more sources
Toxins in Drug Discovery and Pharmacology
Venoms from marine and terrestrial animals (cone snails, scorpions, spiders, snakes, centipedes, cnidarian, etc.) can be seen as an untapped cocktail of biologically active compounds, being increasingly recognized as a new emerging source of peptide ...
Steve Peigneur, Jan Tytgat
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Transcriptomic Insights into the Diversity and Evolution of Myxozoa (Cnidaria, Endocnidozoa) Toxin-like Proteins [PDF]
Myxozoa is a speciose group of endoparasitic cnidarians that can cause severe ecological and economic effects. Their cnidarian affinity is affirmed by genetic relatedness and the presence of nematocysts, historically called “polar capsules”.
Bin Xiao+3 more
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Cnidaria constitute an important phylum of venomous animals, several of which have a significant impact on human health and activities. Cnidarian venoms are included in a special capsule called nematocyst, and are known to consist of peptides, proteins ...
Nurçin Killi+3 more
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Marine Toxins Targeting Kv1 Channels: Pharmacological Tools and Therapeutic Scaffolds
Toxins from marine animals provide molecular tools for the study of many ion channels, including mammalian voltage-gated potassium channels of the Kv1 family.
Rocio K. Finol-Urdaneta+5 more
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Venomics Reveals the Venom Complexity of Sea Anemone Heteractis magnifica [PDF]
The venoms of various sea anemones are rich in diverse toxins, which usually play a dual role in capturing prey and deterring predators. However, the complex components of such venoms have not been well known yet.
Ming Li+7 more
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