Results 101 to 110 of about 23,703 (223)
Small Methods, EarlyView.A fractionation‐free SAXS approach quantifies protein corona formation on silica nanoparticles under native conditions. By deconvoluting scattering from free and bound proteins, adsorbed mass is directly determined in simple and complex media. The method resolves adsorption regimes and thermodynamics, establishing non‐invasive, in situ characterization
Juliana T. T. Carvalho +6 more
wiley +1 more source
2D gel analysis on CNP-overexpressing mouse brain [PDF]
, 2002 2',3'-Cyclic nucleotide 3 '-phosphodiesterase (CNP) is an early marker for oligodendrocytes, and it is suspected to be implicated in the expansion of membranes during myelination.
Malak, Ramez
core
Strategies for enhancing sensitivity in lateral flow assays
VIEW, EarlyView.Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed +3 more
wiley +1 more source
Effect of CNP-53 on bone turnover markers. [PDF]
, 2018 (A) Plasma osteocalcin levels, and (B) plasma TRAP5b levels. The values are the means + SE. Open bars, vehicle (n = 5 in both genotypes); closed bars, CNP-53 (0.5 mg/kg/day, n = 6 in both genotypes). KO, CNP-KO rats; WT, WT rats. *, p p t-test.
Keisho Hirota (4994384) +19 more
core +1 more source
Wildlife Letters, EarlyView.Many nocturnal animals are difficult to study because they are rarely seen, including nocturnal primates, galagos and pottos, in West Africa. Working with over 600 people in 52 villages in southern Guinea‐Bissau, we found that communities frequently recognized galagos by their red eyeshine and distinctive calls, while pottos were not known.
Chloe Chesney +6 more
wiley +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
British Journal of Pharmacology, EarlyView.It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
Characterisation of the anti-inflammatory and anti-proliferative effects of natriuretic peptides in rodents. [PDF]
, 2007 Natriuretic peptides are a family of vasoactive hormones that play important roles in cardiovascular homeostasis. These peptides exert biological effects primarily via activation of guanylate cyclase (GC)-coupled natriuretic peptide receptors (NPR) that ...
Panayiotou, C.M.
core
Endothelium-independent effect of CNP on vascular reactivity. [PDF]
, 2016 Endothelium-independent effect of CNP on vascular reactivity.
Carolina Caniffi (444744) +5 more
core +1 more source
New biosensors and transgenic mice for multiplex cGMP imaging
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source
Measuring integration in adults with chronic non-malignant pain (CNP) [PDF]
, 2008 Despite advances in understanding pain processes, chronic non-malignant pain (CNP) remains a complex and challenging condition which affects all aspects of the sufferer's life.
Deshaies, Kathryn
core +1 more source