Results 31 to 40 of about 1,192 (126)

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, Volume 13, Issue 35, 24 June 2026.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

A note on the potential of CNSL in fuel blends for engines in Brazil

Revista Tecnologia, 2016
CNSL is a by-product of the cashew industry which is the pericarp fluid of the nut. Main producers (India, Nigeria and Brazil) cannot store CNSL as a commodity. The international consumers market is unstable. Thus there is a potential for the use of CNSL
Fernando José Araújo da Silva
doaj   +2 more sources

Preparation and Characterization of Chitosan/Montmorillonite (MMT) Nanocomposite Systems

International Journal of Technology, 2014
A natural- based nanocomposite film consisting of chitosan, montmorillonite (MMT) and cashew nut shell liquid (CNSL) was synthesized. The nanocomposite was prepared by mixing a suspension of clay particles (filler, MMT) with a solution containing ...
Hery Haerudin, Andika W. Pramono, Dona Sulistia Kusuma, Aisyiyah Jenie, Nicolas H. Voelcker, Christopher Gibson   +5 more
doaj   +1 more source

In vitro gas production kinetics and digestibility in ruminant diets with different levels of cashew nut shell liquid

Semina: Ciências Agrárias, 2018
The aim of this study was to evaluate the effect of increasing levels of cashew nut shell liquid (CNSL) in ruminant diets on in vitro dry matter digestibility (IVDMD), gas production kinetics, ruminal fermentation parameters, ammoniacal nitrogen ...
Tatiana García Díaz, Antonio Ferriani Branco, Luís Carlos Vinhas Ítavo, Geraldo Tadeu dos Santos, Silvana Teixeira Carvalho, Ana Lúcia Teodoro, Ronaldo Lopes Oliveira   +6 more
doaj   +3 more sources

Performance and Emission Analysis of a Diesel Engine Fueled with Cashew Nut Shell-Derived Biodiesel and Its Blends

Engineering Proceedings
Cashew nut shell liquid (CNSL) is a byproduct of cashew processing that has largely been overlooked as a biomass resource for biodiesel production. While some research has been conducted on CNSL in diesel engines, there remains a lack of studies on using
S. Jacob, Mohd Majid, S. C. V. Ramana Murty Naidu, Ch. Siva Ramakrishna, N. Punitha, S. Padmanabhan, Naseem Khayum, Anil Singh Yadav, Abhishek Sharma   +8 more
doaj   +1 more source

Evaluation of physico-mechanical characteristics of cashew nut shell liquid-epoxy composites with Borassus and Tamarind fruit fibres as reinforcements

Journal of Natural Fibers, 2019
In this study, Cashew Nut Shell Liquid (CNSL)-epoxy matrix-based composites reinforced with borassus and tamarind fibres were fabricated using compression moulding technique. Three different types of composites were fabricated, namely Borassus fruit fine
Suhas Yeshwant Nayak, Srinivas Shenoy Heckadka, Linto George Thomas   +2 more
doaj   +1 more source

Evaluation of Carbon Nanoparticle Suspension and Methylene Blue Localization for Preoperative Localization of Nonpalpable Breast Lesions: A Comparative Study

Frontiers in Surgery, 2021
Background: The resection of nonpalpable breast lesions (NPBLs) largely depends on the preoperative localization technology. Although several techniques have been used for the guidance of NPBL resection, more comfortable and effective methods are needed.
Yeqing Zhou, Yeqing Zhou, Yiran Liang, Jianshu Zhang, Yang Feng, Xiaoyan Li, Xiaoli Kong, Tingting Ma, Liyu Jiang, Qifeng Yang, Qifeng Yang, Qifeng Yang   +11 more
doaj   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1309-1325, May 2026.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source