Results 211 to 220 of about 67,701 (309)
Impact of Respiratory Support Strategies on CO2 Variability During Therapeutic Hypothermia in Neonates With Asphyxia: Data From the German Hypothermia Registry
Acta Paediatrica, EarlyView.ABSTRACT Aim
To evaluate associations between respiratory support strategies, partial pressure of carbon dioxide (pCO2) variability and oxygen exposure in neonates with hypoxic–ischaemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Methods
This retrospective multicentre study used data from the German Hypothermia Registry, including ...Sebiha Demir, Anne Groteklaes, Bettina Bohnhorst, Kirsten Glaser, Andreas Müller, Hemmen Sabir, Till Dresbach, on behalf of the German Hypothermia Registry, Milian Brasche, Nicolas Allgaier, Daniel Klotz, Norbert Teig, Katja Schneider, Hemmen Sabir, Sandra Holz, Birte Tröger, Thorsten Körner, Uwe Höpner, Marie Schmenk, Michael Hofmann, Mario Rüdiger, Julia Osterholt, Martin Berghäuser, Christopher Willerscheidt, Farina Morgenroth, Hans Jörg Bittrich, Steven Hébert, Arber Arapi, Anja Stein, Veit Lange, Gunnar Rau, Lisa‐Marie Stoek, Nikolas Hillenbrand, Matthias Reger, Susanne Schade, Jana Dieks, Heimke von Osten, Marita Horstkemper, Martin Blohm, Mario Lange, Bettina Bohnhorst, Manuela Friederike Richter, Simon Kranig, Maurice Petrasch, Nasenien Nourkami‐Tutdibi, Christine Pinkwart, Thomas Kriebel, Silvia Welcker, Nora Bonney, Angela Kribs, Clemens Andrée, Sophia Stadermann, Kirsten Glaser, Peter Jahn, Katrin Braun, Anna Eisenhardt, Alba Perez‐Ortiz, Nadine Mand, Ines Wallot, Timea Takacs, Anja Jäger, Oliver Schroers, Esther Schouten, Claudia Nussbaum, Kai Böckenholt, Rüdiger Wentzell, Guido Engelmann, Katherine Louise Kastor, Michael Schroth, Matthias Engler, Friederike Eichhorn, Moritz Rohrbach, Fabian Bärtling, Frank Dohle, Matthias Keller, Marion Weber, Verena Lehnerer, Anja Mayer, Marie‐Claire Detemple, Valentin Oellers, Markus Pingel, Friederike Eilbracht, Jutta Adler, Elena Eberle, Karoline Goj, Virginia Toth, Andrea Czoske, Cornelia Wiechers, Christiane Mayer, Anja Schumann, Patrick Salaschek, Janaina Rauch, Kai Hensel, Pia Paul +93 morewiley +1 more sourcePrevalence and Burden of Fatigue Across Disorders of Gut–Brain Interaction: Results From the Rome Foundation Global Epidemiology Study
Alimentary Pharmacology &Therapeutics, EarlyView.Fatigue is common and burdensome in disorders of gut‐brain interaction and increases with diagnostic overlap. In this global population‐based study, fatigue was associated with female sex, age, BMI, sleep disturbance, higher anxiety and depression scores, greater somatic symptom burden, lower psychological well‐being, antidepressant use, and greater ...Fleur Veldman, Francesco Innocenti, Imran Aziz, Asma Fikree, Shrikant I. Bangdiwala, Olafur Palsson, Ami D. Sperber, Daniel Keszthelyi +7 morewiley +1 more sourceChromosomal and immune dysregulation underlying granular mitosis in glioblastoma
Brain Pathology, EarlyView.Granular mitosis (GM) morphology is linked to PI3K/PTEN pathway alterations, chromosomal disorganization, and impaired innate immunity. Cells exhibiting GM morphology are associated with localized immune responses within their immediate spatial microenvironment.Rachel Barboza, Xuan Wang, August Lin, Eric Liu, Pramath Kakodkar, Yayuan Zhao, Quinn Le, Christina A. Castellani, Qi Zhang +8 morewiley +1 more sourceDNA Copy Number Profiling in Extracellular Vesicles as Clinical Biomarkers of High-Grade Serous Ovarian Carcinoma. [PDF]
J Extracell VesiclesUekusa R, Yokoi A, Ukai M, Yoshida K, Chattrairat K, Yasui T, Inokuma Y, Kitagawa M, Asano-Inami E, Yoshihara M, Tamauchi S, Yoshikawa N, Niimi K, Matsuzaki J, Ochiya T, Ochiya T, Sood AK, Yamamoto Y, Kajiyama H. +18 moreeuropepmc +1 more sourceInterlaboratory performance testing on EPIC v2.0 CNS tumor profiling demonstrates high reproducibility of tumor classification but reveals the need for harmonized copy number variation reporting
Brain Pathology, EarlyView.Using the Infinium MethylationEPIC v2.0 array and Heidelberg Brain Tumor Classifier v12.8, 24 international laboratories achieved highly reproducible CNS tumor classification (97.9% correct; median β‐correlation r = 0.99), while copy number variation interpretation showed substantial interlaboratory variability, highlighting the need for harmonized CNV Katrin Mauch‐Mücke, Christin Siewert, Lora Dimitrova, Sandra Pohl, Brendan Osberg, Annika K. Wefers, Julia Lorenz, Tanja Rothhammer‐Hampl, Till Acker, Alonso Barrantes‐Freer, Jean Boutonnat, Bérengère Dadone‐Montaudié, Claire Delbridge, Wolfgang Dietmaier, Sebastian Dintner, Hildegard Dohmen, Matthias Dottermusch, Daniel Erny, Katrin B. M. Frauenknecht, Tobias Goschzik, Patrick N. Harter, Daniela Hirsch, Yanghao Hou, Theo F. J. Kraus, Maggie Lee, Friederike Liesche‐Starnecker, Anne Mc Leer, Linea Melchior, Michael Mittelbronn, Wolf C. Müller, Shalima S. Nair, Julia E. Neumann, Pitt Niehusmann, Nicole Pfarr, Torsten Pietsch, Marco Prinz, Markus Rechsteiner, Regina Reimann, Laveniya Satgunaseelan, Veronica Skarpeteig, Anne J. Skjulsvik, Karl Sotlar, Isabelle Vanden Bempt, Erik Vassella, Katharina J. Weber, Gabriel Wasinger, Andreas Waha, Karen Zwaenepoel, Felix Sahm, Markus J. Riemenschneider, David Capper +50 morewiley +1 more sourceSpatial Transcriptomics and Bulk RNA‐Seq Analysis Revealed Molecular Classification of Invasive Lobular Carcinoma
Cancer Science, EarlyView.Spatial transcriptomics and bulk RNA‐seq data analysis revealed the molecular characteristics of invasive lobular carcinoma (ILC). ILC was classified into three clusters: proliferative, immunoreactive, and stromal‐rich, with different prognoses. ABSTRACT
Invasive lobular carcinoma (ILC) is a special type of breast cancer.Momoko Tokura, Jun Nakayama, Hironori Suzuki, Mieko Ochi, Miyaka Umemori, Sho Shiino, Masayuki Yoshida, Shin Takayama, Yasushi Yatabe, Yusuke Yamamoto +9 morewiley +1 more source
