Results 211 to 220 of about 75,040 (259)
Cancer Science, EarlyView.Spatial multi‐omics mapping of hepatic angiomyolipoma reveals that PEComas tightly co‐localize with endothelial cells, which drive autophagic flux in adjacent tumor cells via a paracrine PDGFD–PDGFRB–Ras axis, establishing a compensatory survival network that operates in parallel to canonical TSC–mTOR defects.
Xinyang Liu +9 more
wiley +1 more source
Diagnostic limitations of routine low-coverage CNV-seq in detecting mosaic paternal uniparental disomy in Beckwith-Wiedemann syndrome: a case report. [PDF]
Front Med (Lausanne)Li M, Luo L, Jiao J, Cheng Y.
europepmc +1 more source
Evangelie en maatschappij E + M ; opinieblad voor kaderleden van het CNV
, 1987 Christelijk Nationaal Vakverbond
core
Cancer Science, EarlyView.A customized panel was established for BTC MRD detection. Preoperative ctDNA detection was associated with pathological stage and poorer RFS and OS. Longitudinal monitoring detected ctDNA before radiological recurrence in 72.7% of patients, with a median lead time of 77 days, supporting ctDNA as a complementary prognostic biomarker with CA19‐9 ...
Yoshihito Shinohara +13 more
wiley +1 more source
Identifying Choroidal Neovascularization-Associated Genes with GenePlexus in a Protein-Protein Interaction Network. [PDF]
Life (Basel)Liu L, Zhang Y, Huang F, Bao Y, Zhang J.
europepmc +1 more source
Cancer Science, EarlyView.Spatial transcriptomic profiling of SCLC revealed marked intratumoral heterogeneity, including coexisting neuroendocrine and non‐neuroendocrine states and spatially heterogeneous hypoxia, and identified an MMP12+ macrophage population enriched at hypoxic and necrotic tumor interfaces.
Naozane Nomura +15 more
wiley +1 more source
Identification of Copy Number Variants as a Suspected Cause of Cerebral Small Vessel Disease
Clinical Genetics, EarlyView.Whole‐exome sequencing of 111 patients with suspected familial cerebral small vessel disease (CSVD) identified novel copy number variants in four patients across NOTCH3, LMNB1, and COL4A2, using bioinformatic and molecular techniques. These validated CNVs suggest structural variation is an underrecognized potential causal contributor to monogenic CSVD ...
Solomon K. Guyler +5 more
wiley +1 more source
Cerebral Ventriculomegaly With Abnormality of the Aqueduct of Sylvius: A Case Series
Clinical Genetics, EarlyView.Genetic testing leads to a diagnostic rate of ~30% in a fetal cohort with cerebral ventriculomegaly where the neuropathological examination revealed a stenosis or atresia of the aqueduct of Sylvius. ABSTRACT Fetal cerebral ventriculomegalies are brain anomalies with potentially poor neurodevelopmental prognosis.
Romain Nicolle +20 more
wiley +1 more source