Results 81 to 90 of about 67,701 (309)

Top ASD susceptibility CNV loci. [PDF]

, 2013
aThe boundaries of the ASD susceptibility CNV loci were determined as the midpoint of the 10kb region with a θ>6.5.bRefSeq genes including both protein-coding and non-coding RNA genes, and excluding Pseudogenes. For loci with >3 genes, only the number of
Idan Menashe (35870), Eric C. Larsen (423203), Sharmila Banerjee-Basu (55082)   +2 more
core   +1 more source

CNV Radar: an improved method for somatic copy number alteration characterization in oncology

BMC Bioinformatics, 2020
Background Cancer associated copy number variation (CNV) events provide important information for identifying patient subgroups and suggesting treatment strategies.
David Soong, Jeran Stratford, Herve Avet-Loiseau, Nizar Bahlis, Faith Davies, Angela Dispenzieri, A. Kate Sasser, Jordan M. Schecter, Ming Qi, Chad Brown, Wendell Jones, Jonathan J. Keats, Daniel Auclair, Christopher Chiu, Jason Powers, Michael Schaffer   +15 more
doaj   +1 more source

RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine

Advanced Science, EarlyView.
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López‐Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan   +12 more
wiley   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Thai CNV database. [PDF]

, 2014
a) A screen-captured image of Thai CNV homepage (http://thaicnv.icbs.mahidol.ac.th/thaicnv/); b) An example of CNV search page. Red and blue lines indicate deletion and duplication CNVs, respectively.
Wallaya Jongjaroenprasert (614574), Wasan Chantratita (614576), Natini Jinawath (247165), Ekawat Pasomsap (614573), Varodom Charoensawan (614578), Bhoom Suktitipat (202143), Wuttichai Mhuantong (614570), Thitima Tularak (614571), Chaiwat Naktang (614569), Suthat Fuchareon (614575), Paramita Artiwet (614572), Boonsit Yimwadsana (614577), Surakameth Mahasirimongkol (126944)   +12 more
core   +1 more source

Evaluation of Idiopathic Choroidal Neovascularization with Indocyanine Green Angiography in Patients Undergoing Bevacizumab Therapy

Journal of Ophthalmology, 2015
Purpose. To examine the clinical implications of change in choroidal neovascularization (CNV) size on indocyanine green (ICG) angiography in subjects with idiopathic CNV undergoing bevacizumab therapy. Methods.
Ryan B. Rush, Sloan W. Rush
doaj   +1 more source

A Snapshot of CNVs in the Pig Genome

PLoS ONE, 2008
Recent studies of mammalian genomes have uncovered the extent of copy number variation (CNV) that contributes to phenotypic diversity, including health and disease status. Here we report a first account of CNVs in the pig genome covering part of the chromosomes 4, 7, 14, and 17 already sequenced and assembled.
João Fadista, João Fadista, Marianne Nygaard, Lars-Erik Holm, Bo Thomsen, Christian Bendixen   +5 more
openaire   +5 more sources

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Distribution of known miRNA within CNV and non-CNV genes among 8 different species. [PDF]

, 2013
Distribution of known miRNA within CNV and non-CNV genes among 8 different species.
Kyriacos Felekkis (491527), Harsh Dweep (104858), Constantinos Deltas (333799), Konstantinos Voskarides (333789), George D. Georgiou (491526), Norbert Gretz (14081)   +5 more
core   +1 more source

Cognitive Evoked Potentials P300 And CNV In Patients' With Parkinson Disease

Revista Cubana de Investigaciones Biomédicas, 2019
Introduction: A descriptive and traverse study was performed in patients with Parkinson's disease of the Neurology and Neurophysiology department of the Santiago General Hospital "Dr.
Iván Delgado Suárez, Arquímedes Montoya Pedrón, Lianne Alicia Chang Arraño   +2 more
doaj