Results 71 to 80 of about 75,040 (259)
In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma
Advanced Science, EarlyView.By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He +20 more
wiley +1 more source
Journal of Ophthalmology, 2015 Purpose. To examine the clinical implications of change in choroidal neovascularization (CNV) size on indocyanine green (ICG) angiography in subjects with idiopathic CNV undergoing bevacizumab therapy. Methods.
Ryan B. Rush, Sloan W. Rush
doaj +1 more source
Differences of CNV resolution between adults and children: developmental changes in P300
, 2003 脳の事象関連電位である随伴性陰性変動（CNV）の解消過程の発達的変化及び随伴性陰性変動解消過程におけるP300の影響を捉えるため，成人７名と児童８名のCNV解消時問，P300を測定し比較した．そして，P300とCNV解消過程の相関を検討した． その結果，CNV解消時間は，Fzにおいて成人群が児童群よりも有意にCNV解消時間が短かった ...
船瀬, 広三 +2 more
core
Early contingentnegative variation of the EEG and attentional flexibility are reduced in hypotension [PDF]
, 2002 This study explored the question as to whether hypotension is related to decreased attentional performance and reduced cortical activation. A total of 50 females aged 19 44 years participated in the study. Attentional performance was assessed using three
Duschek, Stefan +9 more
core +1 more source
Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen +8 more
wiley +1 more source
Cognitive Evoked Potentials P300 And CNV In Patients' With Parkinson Disease
Revista Cubana de Investigaciones Biomédicas, 2019 Introduction: A descriptive and traverse study was performed in patients with Parkinson's disease of the Neurology and Neurophysiology department of the Santiago General Hospital "Dr.
Iván Delgado Suárez +2 more
doaj
Journal of Ophthalmology, 2016 Purpose. To describe the morphological characteristics and efficacy of OCTA in detecting CNV in nAMD. We retrospectively reviewed 53 patients (86 eyes) with suspected CNV secondary to wet AMD.
Jingwen Gong +4 more
doaj +1 more source
CNV Radar: an improved method for somatic copy number alteration characterization in oncology
BMC Bioinformatics, 2020 Background Cancer associated copy number variation (CNV) events provide important information for identifying patient subgroups and suggesting treatment strategies.
David Soong +15 more
doaj +1 more source
Characterization and Analysis of PHEX Variants in Patients With Hypophosphatemia in Argentina
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Confirming the underlying molecular etiology of hereditary hypophosphatemia (HH) to provide recurrence risk counseling is highly important. Our aims were to describe the detected variants and their distribution across Argentina and to contrast them with published data.
Silvia Ávila +3 more
wiley +1 more source