Results 51 to 60 of about 72,857 (290)

Aqueous Levels of Pigment Epithelium-Derived Factor and Macular Choroidal Thickness in High Myopia

Journal of Ophthalmology, 2015
Purpose. To investigate the correlation between aqueous and serum levels of pigment epithelium-derived factor (PEDF) and macular choroidal thickness in high myopia patients, both with and without choroidal neovascularization (CNV). Methods.
Wei Chen, Yubo Guan, Guanghui He, Zhiwei Li, Hui Song, Shiyong Xie, Quanhong Han   +6 more
doaj   +1 more source

Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization

eLife, 2020
NLRP3 inflammasome activation and complement-mediated inflammation have been implicated in promoting choroidal neovascularization (CNV) in age-related macular degeneration (AMD), but central questions regarding their contributions to AMD pathogenesis ...
Jakob Malsy, Andrea C Alvarado, Joseph O Lamontagne, Karin Strittmatter, Alexander G Marneros   +4 more
doaj   +1 more source

In vivo evaluation of laser-induced choroidal neovascularization in rats simultaneously using optical coherence tomography and photoacoustic microscopy

Journal of Innovative Optical Health Sciences, 2021
Determination of the precise location and the degree of the Choroidal neovascularization (CNV) lesion is essential for diagnosation Neovascular age-related macular degeneration (AMD) and evaluation the efficacy of treatment.
Fengxian Du, Lei Gao, Lin Li, Qian Li, Fenghua Wang, Chuanqing Zhou, Cuixia Dai   +6 more
doaj   +1 more source

Gender differences in CNV burden do not confound schizophrenia CNV associations [PDF]

Scientific Reports, 2016
AbstractCompared with the general population, an excess of rare copy number variants (CNVs) has been identified in people with schizophrenia. Females with neurodevelopmental disorders and in the general population have been reported to carry more large, rare CNVs than males.
Jun Han, James T. R. Walters, George Kirov, Andrew Pocklington, Valentina Escott-Price, Michael J. Owen, Peter Holmans, Michael C. O’Donovan, Elliott Rees   +8 more
openaire   +3 more sources

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

Advanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li, Kelly Yichen Li, Chiara Nicoletti, Stephen Kwok‐Wing Tsui, Pier Lorenzo Puri, Qin Cao, Kevin Y. Yip   +6 more
wiley   +1 more source

Vascular maturity of type 1 and type 2 choroidal neovascularization evaluated by optical coherence tomography angiography.

PLoS ONE, 2019
PurposeVessel maturation is considered to proceed by pruning branches resulting in less branching vessels. This study investigated the vessel junction densities of type 1 and type 2 choroidal neovascularizations (CNVs) using optical coherence tomography ...
Yuyako Nakano, Keiko Kataoka, Jun Takeuchi, Ai Fujita, Hiroki Kaneko, Hideyuki Shimizu, Yasuki Ito, Hiroko Terasaki   +7 more
doaj   +1 more source

The difference in average sensitivities between the inside and outside of CVH (⊿RSo-i) in eyes with CNV (CNV+, n = 6) or without CNV (CNV−, n = 6).

, 2022
The difference in average sensitivities between the inside and outside of CVH (⊿RSo-i) in eyes with CNV (CNV+, n = 6) or without CNV (CNV−, n = 6).
Yoko Nomura (318252), Kohei Ueda (3627656), Keiko Azuma (5204660), Ryo Obata (535491), Rion Ozawa (13155216), Kohdai Kitamoto (13020546), Tatsuya Inoue (2031706), Hiroshi Murata (387321), Ryo Asaoka (387326)   +8 more
core   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

Advanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui, Lulu Qian, Binbin Chu, Xuan Qin, Menglin Wu, Minke Wu, Tongyu He, Baochuan Zhang, Bin Song, Yao He   +9 more
wiley   +1 more source

Early contingentnegative variation of the EEG and attentional flexibility are reduced in hypotension [PDF]

, 2002
This study explored the question as to whether hypotension is related to decreased attentional performance and reduced cortical activation. A total of 50 females aged 19 44 years participated in the study. Attentional performance was assessed using three
Duschek, Stefan, Stefan Duschek, Nathan Weisz, Schandry, Rainer, Jean-Paul Mialet, Rainer Schandry, Jacobs, Arthur M., Arthur M Jacobs, Weisz, Nathan, Mialet, Jean-Paul   +9 more
core   +1 more source

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

Advanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu, Qianru Zhang, Wenqiang Yan, Lu Sun, Yiran Cui, Bolin Liu, Guoqing Han, Feng Zhang, Ke Pu, Mingchao Zhang, Xiaobing Zhang, Qingguo Li, Gang An, Yuxuan Liu   +13 more
wiley   +1 more source