Results 31 to 40 of about 4,048 (215)
STRUCTURAL VARIABLITY OF LEUCOCYTE GENOME AND ARTERIAL CELLS IN HUMAN ATHEROSCLEROSIS
Российский кардиологический журнал, 2017 The review is focused on current views on the structural variation of genome of somatic cells as components related to atherosclerosis. The original data presented on the variation spectrum of DNA areas copies in peripheral blood leucocytes and arterial ...
А. A. Sleptsov +2 more
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British Journal of Ophthalmology, 2001 Editor,—We thank Ergun and Stur1 for their interest in our paper and agree with their comments that it is not possible to directly compare a pilot study with the results of a randomised controlled study. We also pointed out in our conclusion that studies such …
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Biology Open, 2020 Vascular endothelial growth factor (VEGF) is a crucial stimulator for choroidal neovascularization (CNV). Our aim was to develop a reproducible and valid treatment-naive quiescent CNV (i.e.
Shan Liu +5 more
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CNVs in neuropsychiatric disorders [PDF]
Human Molecular Genetics, 2015 Over the last few years at least 11 copy number variations (CNVs) have been shown convincingly to increase risk to developing schizophrenia: deletions at 1q21.1, NRXN1, 3q29, 15q11.2, 15q13.3 and 22q11.2, and duplications at 1q21.1, 7q11.23, 15q11.2-q13.1, 16p13.1 and proximal 16p11.2.
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
An Attempt to Find Alternative Stains for Routine Hematoxylin and Eosin
RGUHS Journal of Medical SciencesBackground Universally accepted stains for the routine histopathological examination are Hematoxylin and Eosin. There are even special stains that would specifically stain the individual tissue architecture such as stains for ...
Ram Kumar Tirandas, Akhila CNV
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CNVs in neurodevelopmental disorders
Oncotarget, 2015 Copy number variations (CNVs) consist of duplications or deletions of chromosomal regions ranging from a few hundred to more than a million bases in size, and are likely to play a role in phenotypic diversity and evolution. Recent advances in the identification and mapping of CNVs among normal individuals and in model systems, using bioinformatics and ...
Chun-Ting, Lee +2 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Adhesion failures determine the pattern of choroidal neovascularization in the eye: a computer simulation study. [PDF]
PLoS Computational Biology, 2012 Choroidal neovascularization (CNV) of the macular area of the retina is the major cause of severe vision loss in adults. In CNV, after choriocapillaries initially penetrate Bruch's membrane (BrM), invading vessels may regress or expand (CNV initiation ...
Abbas Shirinifard +6 more
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