Results 31 to 40 of about 75,040 (259)
Adhesion failures determine the pattern of choroidal neovascularization in the eye: a computer simulation study. [PDF]
PLoS Computational Biology, 2012 Choroidal neovascularization (CNV) of the macular area of the retina is the major cause of severe vision loss in adults. In CNV, after choriocapillaries initially penetrate Bruch's membrane (BrM), invading vessels may regress or expand (CNV initiation ...
Abbas Shirinifard +6 more
doaj +1 more source
JAX-CNV: A Whole-genome Sequencing-based Algorithm for Copy Number Detection at Clinical Grade Level
Genomics, Proteomics & Bioinformatics, 2022 We aimed to develop a whole-genome sequencing (WGS)-based copy number variant (CNV) calling algorithm with the potential of replacing chromosomal microarray assay (CMA) for clinical diagnosis.
Wan-Ping Lee +10 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Effects of Copy Number Variations on Developmental Aspects of Children With Delayed Development [PDF]
Annals of Rehabilitation Medicine, 2019 Objective To determine effects of copy number variations (CNV) on developmental aspects of children suspected of having delayed development. Methods A retrospective chart review was done for 65 children who underwent array-comparative genomic ...
Kee-Boem Park +5 more
doaj +1 more source
Unambiguously phased CNV regions in families.
, 2015 Percentage of CNV regions in HapMap YRI and EGCUT families where PiCNV was automatically able to unambiguously determine the underlying normal and CNV-carrying haplotypes in parents and follow their transmission in offspring.
Priit Palta (116414) +9 more
core +1 more source
FEBS Open Bio, EarlyView.Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Advanced Science, EarlyView.Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li +6 more
wiley +1 more source
Multimodal imaging of laser-induced choroidal neovascularization in pigmented rabbits
Scientific Reports, 2023 This study aimed to demonstrate longitudinal multimodal imaging of laser photocoagulation-induced choroidal neovascularization (CNV) in pigmented rabbits. Six Dutch Belted pigmented rabbits were treated with 12 laser lesions in each eye at a power of 300
Van Phuc Nguyen +5 more
doaj +1 more source
Factors associated with the recurrence of choroidal neovascularization in pathologic myopia
Frontiers in Medicine, 2022 PurposeTo investigate the factors associated with the recurrence of pathologic myopia choroidal neovascularization (PM-CNV).MethodsForty-eight eyes of 48 patients with PM-CNV treated with conbercept at least 6 months of follow-up were included ...
Ruixia Jing +3 more
doaj +1 more source
OOMMF extension: Dzyaloshinskii-Moriya interaction (DMI) for the crystallographic class Cnv
, 2018 <p>OOMMF extension: Dzyaloshinskii-Moriya interaction (DMI) for the crystallographic class Cnv.</p ...
Marijan Beg (5285053) +9 more
core +1 more source